ELISA Kit for Mouse Hypoxia-inducible factor 1-alpha inhibitor

Mfr.No.	E0495m
Alternative Names	Hypoxia-inducible factor asparagine hydroxylase
Categories	Elisa
Function	Hydroxylates HIF-1 alpha at 'Asp-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
Specificity	Natural and recombinant Mouse Hypoxia-inducible factor 1-alpha inhibitor
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	HIF1N_MOUSE
Method Type	Sandwich
Platform	PF08007
Protein Name	Hypoxia-inducible factor 1-alpha inhibitor
Sensitivity	0.168ng/mL
Sequence	50: MAATAAEVAA ; SGSGEAREEA ; EAPGPAWDES ; QLRSYSFPTR ; PIPRLSQSDP ; 100: RAEELIENEE ; PVVLTDTNLV ; YPALKWDLEY ; LQENIGNGDF ; SVYSASTHKF ; 150: LYYDEKKMGN ; FQNFKPRSNR ; EEIKFHEFVE ; KLQAIQQRGG ; EERLYLQQTL ; 200: NDTVGRKIVM ; DFLGFNWNWI ; NKQQGKRGWG ; QLTSNLLLIG ; MEGNVTPAHY ; 250: DEQQNFFAQI ; KGHKRCILFP ; PDQFECLYPY ; PVHHPCDRQS ; QVDFDNPDYE ; 300: RFPNFRNVVG ; YETVVGPGDV ; LYIPMYWWHH ; IESLLNGGIT ; ITVNFWYKGA ; 349: PTPKRIEYPL ; KAHQKVAIMR ; NIEKMLGEAL ; GNPQEVGPLL ; NTMIKGRYN
Sequence Length	349
String	Q8BLR9
Sub Unit	Homodimer. Interacts with VHL and HIF1A.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804768	E0495m	96T	$776		Add to Cart