ELISA Kit for Mouse Histone H3.3C

Mfr.No.	E8172m
Alternative Names	Embryonic ; Gm14384
Categories	Elisa
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Specificity	Natural and recombinant Mouse Histone H3.3C
Subcellular Location	Nucleus Chromosome
Entryname	H3C_MOUSE
Platform	PF00125
Protein Name	Histone H3.3C
Sequence	50: MAHTKQTARK ; STCGKAPRKQ ; LATKAAXKSA ; PSTGGVKKSH ; RYRPDTVALL ; 100: EIRRYHSTEL ; LIHKLPFQRL ; VQEIAQDFKT ; DLRFQSAAIG ; ALQEASEANR ; 135: VGLFEDTNLC ; AIHAKCVTVI ; PKDIQLAHSI ; LGERA
Sequence Length	135
Sub Unit	The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

Reference	1. "Isolation of two clusters of mouse histone genes." Sittman D.B., Chiu I.-M., Pan C.-J., Cohn R.H., Kedes L.H., Marzluff W.F. Jr. Proc. Natl. Acad. Sci. U.S.A.78:4078-4082(1981) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805262	E8172m	96T	$776		Add to Cart