ELISA Kit for Mouse Fibroblast growth factor 8

Mfr.No.	E2137m
Alternative Names	Androgen-induced growth factor ; AIGF ; Heparin-binding growth factor 8 ; HBGF-8 ; Aigf
Categories	Elisa
Function	Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (By similarity). Cooperates with Wnt-1 in mouse mammary tumor virus-induced murine mammary tumorigenesis.
Specificity	Natural and recombinant Mouse Fibroblast growth factor 8
Subcellular Location	Secreted
Detection Range	31.2-2000pg/mL
Entryname	FGF8_MOUSE
Method Type	Sandwich
Platform	PF00167
Protein Name	Fibroblast growth factor 8
Sensitivity	15.73pg/mL
Sequence	50: MGSPRSALSC ; LLLHLLVLCL ; QAQVRSAAQK ; RGPGAGNPAD ; TLGQGHEDRP ; 100: FGQRSRAGKN ; FTNPAPNYPE ; EGSKEQRDSV ; LPKVTQRHVR ; EQSLVTDQLS ; 150: RRLIRTYQLY ; SRTSGKHVQV ; LANKRINAMA ; EDGDPFAKLI ; VETDTFGSRV ; 200: RVRGAETGLY ; ICMNKKGKLI ; AKSNGKGKDC ; VFTEIVLENN ; YTALQNAKYE ; 250: GWYMAFTRKG ; RPRKGSKTRQ ; HQREVHFMKR ; LPRGHHTTEQ ; SLRFEFLNYP ; 268: PFTRSLRGSQ ; RTWAPEPR
Sequence Length	268
String	P37237
Sub Unit	Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.

Reference	1. "Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells." Tanaka A., Miyamoto K., Minamino N., Takeda M., Sato B., Matsuo H., Matsumoto K. Proc. Natl. Acad. Sci. U.S.A.89:8928-8932(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE 2. "Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis." Macarthur C.A., Shankar D.B., Shackleford G.M. J. Virol.69:2501-2507(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Mammary carcinoma. 3. "A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth." Mahmood R., Bresnick J., Hornbruch A., Mahony C., Morton N., Colquhoun K., Martin P., Lumsden A., Dickson C., Mason I. Curr. Biol.5:797-806(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804085	E2137m	96T	$776		Add to Cart