ELISA Kit for Mouse Fibroblast growth factor 2

Mfr.No.	E0551m
Alternative Names	Basic fibroblast growth factor ; bFGF ; Heparin-binding growth factor 2 ; HBGF-2 ; Fgf-2
Categories	Elisa
Function	Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
Specificity	Natural and recombinant Mouse Fibroblast growth factor 2
Subcellular Location	Secreted Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane.
Detection Range	15.6-1000pg/mL
Entryname	FGF2_MOUSE
Method Type	Sandwich
Platform	PF00167
Protein Name	Fibroblast growth factor 2
Sensitivity	7.89pg/mL
Sequence	50: MAASGITSLP ; ALPEDGGAAF ; PPGHFKDPKR ; LYCKNGGFFL ; RIHPDGRVDG ; 100: VREKSDPHVK ; LQLQAEERGV ; VSIKGVCANR ; YLAMKEDGRL ; LASKCVTEEC ; 150: FFFERLESNN ; YNTYRSRKYS ; SWYVALKRTG ; QYKLGSKTGP ; GQKAILFLPM ; 154: SAKS
Sequence Length	154
String	P15655
Sub Unit	Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2.

Reference	1. "Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis." Hebert J.M., Basilico C., Goldfarb M., Haub O., Martin G.R. Dev. Biol.138:454-463(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. Ma R.Z., Teuscher C. Submitted (1998-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: A/J. strain: C57BL/6J. strain: NOD/LtJ. tissue: Spleen. 3. "Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis." Kurtz A., Wang H.-L., Darwiche N., Harris V., Wellstein A. Oncogene14:2671-2681(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGF2

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13804687	E0551m	96T	$776		Add to Cart