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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Eukaryotic translation initiation factor 2-alpha kinase 3

SKU : BHE13804014

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11434m
Alternative Names	PRKR-like endoplasmic reticulum kinase ; Pancreatic eIF2-alpha kinase ; Pek ; Perk
Categories	Elisa
Function	Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
Specificity	Natural and recombinant Mouse Eukaryotic translation initiation factor 2-alpha kinase 3
Subcellular Location	Endoplasmic reticulum membrane Single-pass type I membrane protein
Detection Range	0.312-20ng/mL
Entryname	E2AK3_MOUSE
Method Type	Sandwich
Platform	PF00069
Protein Name	Eukaryotic translation initiation factor 2-alpha kinase 3
Sensitivity	0.161ng/mL
Sequence	50: MERATRPGPR ; ALLLLLFLLL ; GCAAGISAVA ; PARSLLAPAS ; ETVFGLGAAA ; 100: APTSAARVPA ; VATAEVTVED ; AEALPAAAGE ; PESRATEPDD ; DVELRPRGRS ; 150: LVIISTLDGR ; IAALDAENDG ; KKQWDLDVGS ; GSLVSSSLSK ; PEVFGNKMII ; 200: PSLDGDLFQW ; DRDRESMEAV ; PFTVESLLES ; SYKFGDDVVL ; VGGKSLITYG ; 250: LSAYSGKLRY ; ICSALGCRRW ; DSDEMEEEED ; ILLLQRTQKT ; VRAVGPRSGS ; 300: EKWNFSVGHF ; ELRYIPDMET ; RAGFIESTFK ; PGGNKEDSKI ; ISDVEEQEAT ; 350: MLDTVIKVSV ; ADWKVMAFSR ; KGGRLEWEYQ ; FCTPIASAWL ; VRDGKVIPIS ; 400: LFDDTSYTAS ; EEALGDEEDI ; VEAARGATEN ; SVYLGMYRGQ ; LYLQSSVRVS ; 450: EKFPTSPKAL ; ESVNGENAII ; PLPTIKWKPL ; IHSPSRTPVL ; VGSDEFDKCL ; 500: SNDKYSHEEY ; SNGALSILQY ; PYDNGYYLPY ; YKRERNKRST ; QITVRFLDSP ; 550: HYSKNIRKKD ; PILLLHWWKE ; IFGTILLCIV ; ATTFIVRRLF ; HPQPHRQRKE ; 600: SETQCQTESK ; YDSVSADVSD ; NSWNDMKYSG ; YVSRYLTDFE ; PIQCMGRGGF ; 650: GVVFEAKNKV ; DDCNYAIKRI ; RLPNRELARE ; KVMREVKALA ; KLEHPGIVRY ; 700: FNAWLETPPE ; KWQEEMDEIW ; LKDESTDWPL ; SSPSPMDAPS ; VKIRRMDPFS ; 750: TKEQIEVIAP ; SPERSRSFSV ; GISCGQTSSS ; ESQFSPLEFS ; GTDCGDNSDS ; 800: ADAAYNLQDS ; CLTDCEDVED ; GTVDGNDEGH ; SFELCPSEAS ; PYTRSREGTS ; 850: SSIVFEDSGC ; GNASSKEEPR ; GNRLHDGNHY ; VNKLTDLKCS ; SSRSSSEATT ; 900: LSTSPTRPTT ; LSLDFTKNTV ; GQLQPSSPKV ; YLYIQMQLCR ; KENLKDWMNR ; 950: RCSLEDREHG ; VCLHIFLQIA ; EAVEFLHSKG ; LMHRDLKPSN ; IFFTMDDVVK ; 1000: VGDFGLVTAM ; DQDEEEQTVL ; TPMPAYATHT ; GQVGTKLYMS ; PEQIHGNNYS ; 1050: HKVDIFSLGL ; ILFELLYPFS ; TQMERVRILT ; DVRNLKFPLL ; FTQKYPQEHM ; 1100: MVQDMLSPSP ; TERPEATDII ; ENAIFENLEF ; PGKTVLRQRS ; RSMSSSGTKH ; 1114: SRQPSCSYSP ; LPGN
Sequence Length	1114
String	Q9Z2B5
Sub Unit	Forms dimers with HSPA5/BIP in resting cells. Oligomerizes in ER-stressed cells. Interacts with DNAJC3.

Uniprot	Q9Z2B5
Gene Name	Eif2ak3
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.247167

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804014	E11434m	96T	$776		Add to Cart

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