ELISA Kit for Mouse Estradiol 17 beta-dehydrogenase 5

Mfr.No.	E0603m
Alternative Names	17-beta-HSD 5 ; Hsd17b5
Categories	Elisa
Function	Active toward androgens, estrogens, and xenobiotic substrates. Also exhibits low 20 alpha-HSD activity. Shows a-stereospecificity in hydrogen transfer between cofactors and substrates (A-specific). Preferentially catalyzes the reduction of 4-androstenedione, 5-alpha-androstane-3,17-dione, androsterone and dehydroepiandrosterone to testosterone, dihydrotestosterone, 5-alpha-androstane-3-alpha,17-beta-diol and 5-androstene-3-beta,17-beta-diol, respectively.
Specificity	Natural and recombinant Mouse Estradiol 17 beta-dehydrogenase 5
Detection Range	0.156-10ng/mL
Entryname	DHB5_MOUSE
Method Type	Sandwich
Platform	PF00248
Protein Name	Estradiol 17 beta-dehydrogenase 5
Sensitivity	0.089ng/mL
Sequence	50: MDSKQQTVRL ; SDGHFIPILG ; FGTYAPQEVP ; KSKATEATKI ; AIDAGFRHID ; 100: SASMYQNEKE ; VGLAIRSKIA ; DGTVKREDIF ; YTSKVWCTFH ; RPELVRVCLE ; 150: QSLKQLQLDY ; VDLYLIHFPM ; AMKPGENYLP ; KDENGKLIYD ; AVDICDTWEA ; 200: MEKCKDAGLA ; KSIGVSNFNR ; RQLEKILKKP ; GLKYKPVCNQ ; VECHPYLNQG ; 250: KLLDFCRSKD ; IVLVAYSALG ; SHREKQWVDQ ; SSPVLLDNPV ; LGSMAKKYNR ; 300: TPALIALRYQ ; LQRGVVVLAK ; SFSEKRIKEN ; MQVFEFQLTS ; EDMKVLDDLN ; 323: KNIRYISGSS ; FKDHPDFPFW ; DEY
Sequence Length	323
String	P70694
Sub Unit	Monomer.

Reference	1. "Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family." Deyashiki Y., Ohshima K., Nakanishi M., Sato K., Matsuura K., Hara A. J. Biol. Chem.270:10461-10467(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS;PARTIAL PROTEIN SEQUENCE strain: BALB/c. tissue: Liver. 2. "Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene." Rheault P., Charbonneau A., Luu-The V. Biochim. Biophys. Acta1447:17-24(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION;TISSUE SPECIFICITY strain: BALB/c. tissue: Leukocyte. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: FVB/N. tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803267	E0603m	96T	$776		Add to Cart