ELISA Kit for Mouse Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein

Mfr.No.	E15335m
Alternative Names	Putative peptidase SRAPD1 ; 3.4.-.- ; SRAP domain-containing protein 1 ; Srapd1
Categories	Elisa
Function	Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells, suggesting that it acts as a specific reader of 5hmC in stem cells (PubMed:23434322). May act as a peptidase; experimental evidences are however required to confirm this prediction.
Specificity	Natural and recombinant Mouse Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein
Detection Range	0.78-50ng/mL
Entryname	HMCES_MOUSE
Method Type	Sandwich
Platform	PF02586
Protein Name	Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein
Sensitivity	0.23ng/mL
Sequence	50: MCGRTSCHLP ; REVLTRACAY ; QDRQGRRRLP ; QWRDPDKYCP ; SYNKSPQSSS ; 100: PVLLSRLHFE ; KDADSSDRII ; IPMRWGLVPS ; WFKESDPSKL ; QFNTTNCRSD ; 150: TIMEKQSFKV ; PLGKGRRCVV ; LADGFYEWQR ; CQGTNQRQPY ; FIYFPQIKTE ; 200: KSGGNDASDS ; SDNKEKVWDN ; WRLLTMAGIF ; DCWEAPGGEC ; LYSYSIITVD ; 250: SCRGLSDIHS ; RMPAILDGEE ; AVSKWLDFGE ; VATQEALKLI ; HPIDNITFHP ; 300: VSPVVNNSRN ; NTPECLAPAD ; LLVKKEPKAN ; GSSQRMMQWL ; ATKSPKKEVP ; 350: DSPKKDASGL ; PQWSSQFLQK ; SPLPAKRGAT ; SSFLDRWLKQ ; EKEDEPMAKK ; 353: PNS
Sequence Length	353

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: FVB/N. tissue: Mammary gland. tissue: Mammary tumor. 2. "Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives." Spruijt C.G., Gnerlich F., Smits A.H., Pfaffeneder T., Jansen P.W., Bauer C., Munzel M., Wagner M., Muller M., Khan F., Eberl H.C., Mensinga A., Brinkman A.B., Lephikov K., Muller U., Walter J., Boelens R., van Ingen H., Leonhardt H., Carell T., Vermeulen M.more... Cell152:1146-1159(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805176	E15335m	96T	$776		Add to Cart