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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Disintegrin and metalloproteinase domain-containing protein 10

SKU : BHE13800628

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0766m
Alternative Names	Kuzbanian protein homolog ; Mammalian disintegrin-metalloprotease ; CD156c ; Kuz ; Madm
Categories	Elisa
Function	Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP) at '687-Lys- ; -Leu-688'. Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch. May regulate the EFNA5-EPHA3 signaling.
Specificity	Natural and recombinant Mouse Disintegrin and metalloproteinase domain-containing protein 10
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	ADA10_MOUSE
Method Type	Sandwich
Platform	PF00200
Protein Name	Disintegrin and metalloproteinase domain-containing protein 10
Sensitivity	0.081ng/mL
Sequence	50: MVLPTVLILL ; LSWAAGLGGQ ; YGNPLNKYIR ; HYEGLSYNVD ; SLHQKHQRAK ; 100: RAVSHEDQFL ; LLDFHAHGRQ ; FNLRMKRDTS ; LFSDEFKVET ; SNKVLDYDTS ; 150: HIYTGHIYGE ; EGSFSHGSVI ; DGRFEGFIKT ; RGGTFYIEPA ; ERYIKDRILP ; 200: FHSVIYHEDD ; INYPHKYGPQ ; GGCADHSVFE ; RMRKYQMTGV ; EEGARAHPEK ; 250: HAASSGPELL ; RKKRTTLAER ; NTCQLYIQTD ; HLFFKYYGTR ; EAVIAQISSH ; 300: VKAIDTIYQT ; TDFSGIRNIS ; FMVKRIRINT ; TSDEKDPTNP ; FRFPNIGVEK ; 350: FLELNSEQNH ; DDYCLAYVFT ; DRDFDDGVLG ; LAWVGAPSGS ; SGGICEKSKL ; 400: YSDGKKKSLN ; TGIITVQNYG ; SHVPPKVSHI ; TFAHEVGHNF ; GSPHDSGTEC ; 450: TPGESKNLGQ ; KENGNYIMYA ; RATSGDKLNN ; NKFSLCSIRN ; ISQVLEKKRN ; 500: NCFVESGQPI ; CGNGMVEQGE ; ECDCGYSDQC ; KDDCCFDANQ ; PEGKKCKLKP ; 550: GKQCSPSQGP ; CCTAQCAFKS ; KSEKCRDDSD ; CAKEGICNGF ; TALCPASDPK ; 600: PNFTDCNRHT ; QVCINGQCAG ; SICEKYDLEE ; CTCASSDGKD ; DKELCHVCCM ; 650: KKMAPSTCAS ; TGSLQWSKQF ; SGRTITLQPG ; SPCNDFRGYC ; DVFMRCRLVD ; 700: ADGPLARLKK ; AIFSPQLYEN ; IAEWIVAHWW ; AVLLMGIALI ; MLMAGFIKIC ; 749: SVHTPSSNPK ; LPPPKPLPGT ; LKRRRPPQPI ; QQPPRQRPRE ; SYQMGHMRR
Sequence Length	749
String	O35598
Sub Unit	Forms a ternary EFNA5-EPHA3-ADAM10 complex mediating EFNA5 extracellular domain shedding by ADAM10 which regulates the EFNA5-EPHA3 complex internalization and function (By similarity). Interacts with EPHA2.

Uniprot	O35598
Gene Name	Adam10
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:11487
Unigene	Mm.3037

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800628	E0766m	96T	$776		Add to Cart

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