Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
Specificity
Natural and recombinant Mouse D(2) dopamine receptor
Subcellular Location
Cell membrane Multi-pass membrane protein
Detection Range
0.312-20ng/mL
Entryname
DRD2_MOUSE
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of DRD2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤7.9%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤10.8%
Protein Name
D(2) dopamine receptor
Recovery
Recovery was determined by spiking various levels of DRD2 into serum and plasma .
Forms homo- and heterooligomers with DRD4. The interaction with DRD4 may modulate agonist-induced downstream signaling. Interacts with GPRASP1, PPP1R9B, CADPS, CADPS2 and CLIC6. Interacts with ARRB2 and GNAI1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 175-270 (ISOFORM 1)