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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse CDK-activating kinase assembly factor MAT1

SKU : BHE13812189

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14238m
Antigen	MNAT1
Alternative Names	CDK7/cyclin-H assembly factor ; Menage a trois ; RING finger protein MAT1 ; p35 ; p36 ; Mat1
Categories	Elisa
Function	Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Specificity	Natural and recombinant Mouse CDK-activating kinase assembly factor MAT1
Subcellular Location	Nucleus
Detection Range	0.156-10ng/mL
Entryname	MAT1_MOUSE
Method Type	Sandwich
Platform	PF06391
Protein Name	CDK-activating kinase assembly factor MAT1
Sensitivity	0.049ng/mL
Sequence	50: MDDQGCPRCK ; TTKYRNPSLK ; LMVNVCGHTL ; CESCVDLLFV ; RGAGNCPECG ; 100: TPLRKSNFRV ; QLFEDPTVDK ; EVEIRKKVLK ; IYNKREEDFP ; SLREYNDFLE ; 150: EVEEIVFNLT ; NNVDLENTKK ; KMEIYQKENK ; DVIQKNKLKL ; TREQEELEEA ; 200: LEVERQEHEQ ; RRLFIQKEEE ; LQQALKRKNK ; QAFLDELESS ; DLPVALLLAQ ; 250: HKDRSTQLEM ; QLEKPRSMKP ; VTFSTGIKMG ; QQISLAPIQK ; LEEALYEYQP ; 300: LQIETCGPQV ; PEQELLGRLG ; YLNHVRAASP ; QDLAGGYTSS ; LACHRALQDA ; 309: FSGLFWQPR
Sequence Length	309
String	P51949
Sub Unit	Associates primarily with CDK7 and cyclin H to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.

Uniprot	P51949
Gene Name	Mnat1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:17420
Unigene	Mm.246750

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812189	E14238m	96T	$776		Add to Cart

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