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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Beta-secretase 2

SKU : BHE13801603

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1812m
Alternative Names	Aspartyl protease 1 ; ASP1 ; Beta-site amyloid precursor protein cleaving enzyme 2 ; Beta-site APP cleaving enzyme 2 ; Memapsin-1 ; Membrane-associated aspartic protease 1 ; Theta-secretase
Categories	Elisa
Function	Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
Specificity	Natural and recombinant Mouse Beta-secretase 2
Subcellular Location	Membrane Single-pass type I membrane protein Golgi apparatus Endoplasmic reticulum Endosome Cell surface
Detection Range	0.312-20ng/mL
Entryname	BACE2_MOUSE
Method Type	Sandwich
Platform	PF00026
Protein Name	Beta-secretase 2
Sensitivity	0.174ng/mL
Sequence	50: MGALLRALLL ; LVLAQWLLSA ; VPALAPAPFT ; LPLQVAGATN ; HRASAVPGLG ; 100: TPELPRADGL ; ALALEPVRAT ; ANFLAMVDNL ; QGDSGRGYYL ; EMLIGTPPQK ; 150: VQILVDTGSS ; NFAVAGAPHS ; YIDTYFDSES ; SSTYHSKGFD ; VTVKYTQGSW ; 200: TGFVGEDLVT ; IPKGFNSSFL ; VNIATIFESE ; NFFLPGIKWN ; GILGLAYAAL ; 250: AKPSSSLETF ; FDSLVAQAKI ; PDIFSMQMCG ; AGLPVAGSGT ; NGGSLVLGGI ; 300: EPSLYKGDIW ; YTPIKEEWYY ; QIEILKLEIG ; GQNLNLDCRE ; YNADKAIVDS ; 350: GTTLLRLPQK ; VFDAVVEAVA ; RTSLIPEFSD ; GFWTGAQLAC ; WTNSETPWAY ; 400: FPKISIYLRD ; ENASRSFRIT ; ILPQLYIQPM ; MGAGFNYECY ; RFGISSSTNA ; 450: LVIGATVMEG ; FYVVFDRAQR ; RVGFAVSPCA ; EIEGTTVSEI ; SGPFSTEDIA ; 500: SNCVPAQALN ; EPILWIVSYA ; LMSVCGAILL ; VLILLLLLPL ; HCRHAPRDPE ; 514: VVNDESSLVR ; HRWK
Sequence Length	514
String	Q9JL18
Sub Unit	Monomer. Interacts ith RTN3 and RTN4.

Uniprot	Q9JL18
Gene Name	Bace2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:56175
Unigene	Mm.97885

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801603	E1812m	96T	$776		Add to Cart

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