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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Bcl-2 homologous antagonist/killer

SKU : BHE13801148

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9626m
Alternative Names	Apoptosis regulator BAK ; Bak
Categories	Elisa
Function	In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.
Specificity	Natural and recombinant Mouse Bcl-2 homologous antagonist/killer
Subcellular Location	Mitochondrion membrane Single-pass membrane protein
Entryname	BAK_MOUSE
Platform	PF00452
Protein Name	Bcl-2 homologous antagonist/killer
Sequence	50: MASGQGPGPP ; KVGCDESPSP ; SEQQVAQDTE ; EVFRSYVFYL ; HQQEQETQGR ; 100: PPANPEMDNL ; PLEPNSILGQ ; VGRQLALIGD ; DINRRYDTEF ; QNLLEQLQPT ; 150: AGNAYELFTK ; IASSLFKSGI ; SWGRVVALLG ; FGYRLALYVY ; QRGLTGFLGQ ; 200: VTCFLADIIL ; HHYIARWIAQ ; RGGWVAALNL ; RRDPILTVMV ; IFGVVLLGQF ; 208: VVHRFFRS
Sequence Length	208
String	O08734
Sub Unit	Homodimer. Formation of the homodimer is zinc-dependent. Forms heterodimers with BCL2, E1B 19k protein, and BCL2L1 isoform Bcl-X(L) (By similarity). Interacts with BCL2A1.

Uniprot	O08734
Gene Name	Bak1
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.2443

Reference	1. "Gene structure, cDNA sequence, and expression of murine Bak, a proapoptotic Bcl-2 family member." Ulrich E., Kauffmann-Zeh A., Hueber A.O., Williamson J., Chittenden T., Ma A., Evan G.I. Genomics44:195-200(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Swiss. tissue: Liver. 2. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 3. "Structural plasticity underpins promiscuous binding of the prosurvival protein A1." Smits C., Czabotar P.E., Hinds M.G., Day C.L. Structure16:818-829(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 64-89 IN COMPLEX WITH BCL2A1

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801148	E9626m	96T	$776		Add to Cart

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