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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse B-cell lymphoma 3 protein homolog

SKU : BHE13801568

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1734m
Categories	Elisa
Function	Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit (By similarity). In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation.
Specificity	Natural and recombinant Mouse B-cell lymphoma 3 protein homolog
Subcellular Location	Nucleus Cytoplasm Cytoplasm perinuclear region Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation.
Detection Range	31.2-2000pg/mL
Entryname	BCL3_MOUSE
Method Type	Sandwich
Platform	PF00023
Protein Name	B-cell lymphoma 3 protein homolog
Sensitivity	15.6pg/mL
Sequence	50: MPRCPAGAMD ; EGPVDLRTRP ; KGTPGAALPL ; RKRPLRPASP ; EPATTRSPAG ; 100: PLDALRSGCD ; VPVVPGPPHC ; VARPEALYYQ ; GPLMPIYSTP ; TMAPHFPLLN ; 150: LPTHPYSMIC ; PMEHPLSADI ; AMATRVDEDG ; DTPLHIAVVQ ; NNIAAVYRIL ; 200: SLFKLGSREV ; DVHNNLRQTP ; LHLAVITTLP ; DMVRLLVTAG ; ASPMALDRHG ; 250: QTAIHLACEH ; RSPSCLQALL ; DSATSGSVDL ; EVRNYEGLTA ; LHVAVNTGCQ ; 300: EAVLLLLERG ; ADIDAVDIKS ; GRSPLIHAVE ; NNSLNMVQLL ; LLHGANVNAQ ; 350: MYSGSSALHS ; ASGRGLLPLV ; RTLVRSGADS ; GLKNCHNDTP ; LMVARSRRVI ; 400: DILRGKASRA ; ASGSQPEPSP ; DQSATNSPES ; SSRLSSNGLQ ; SSPSSSPSLS ; 448: PPKDAPGFPA ; TPQNFFLPTT ; STPAFLPFPG ; VLRGPGRPVP ; PSPAPGSS
Sequence Length	448
String	Q9Z2F6
Sub Unit	Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2, COPS5 and PIR (By similarity). Interacts with CYLD.

Uniprot	Q9Z2F6
Gene Name	Bcl3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:12051
Unigene	Mm.439658

Reference	1. "Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.more... PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: C57BL/6J. 2. "Interleukin-9 regulates NF-kappaB activity through BCL3 gene induction." Richard M., Louahed J., Demoulin J.-B., Renauld J.-C. Blood93:4318-4327(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C57BL/6. 3. "Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling." Massoumi R., Chmielarska K., Hennecke K., Pfeifer A., Fassler R. Cell125:665-677(2006) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CYLD;SUBCELLULAR LOCATION 4. "CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin." Wickstrom S.A., Masoumi K.C., Khochbin S., Fassler R., Massoumi R. EMBO J.29:131-144(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CYLD

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801568	E1734m	96T	$776		Add to Cart

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