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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse ATP-dependent RNA helicase DDX42

SKU : BHE13803629

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14799m
Alternative Names	DEAD box protein 42
Categories	Elisa
Function	ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
Specificity	Natural and recombinant Mouse ATP-dependent RNA helicase DDX42
Subcellular Location	Cytoplasm Nucleus speckle Nucleus Cajal body
Detection Range	31.2-2000pg/mL
Entryname	DDX42_MOUSE
Method Type	Sandwich
Platform	PF00270
Protein Name	ATP-dependent RNA helicase DDX42
Sensitivity	15.78pg/mL
Sequence	50: MNWNKGGPGT ; KRGFGFGGFA ; ISAGKKEEAK ; LPQQSHSAFG ; AASSSSGFGK ; 100: SAPPQLPSFY ; KIGSKRANFD ; EENAYFEDEE ; EDSSNVDLPY ; IPAENSPTRQ ; 150: QFHSKPADSD ; SDDDPLEAFM ; AEVEDQAARD ; MKRLEEKDKE ; RKNVKGIRDD ; 200: IEEEDDQEAY ; FRYMAENPTA ; GVVQEEEEDN ; LEYDSDGNPI ; APSKKIIDPL ; 250: PPIDHSEIDY ; PPFEKNFYNE ; HEEITNLTPQ ; QLIDLRHKLN ; LRVSGAAPPR ; 300: PGSSFAHFGF ; DEQLMHQIRK ; SEYTQPTPIQ ; CQGVPVALSG ; RDMIGIAKTG ; 350: SGKTAAFIWP ; MLIHIMDQKE ; LEPGDGPIAV ; IVCPTRELCQ ; QIHAECKRFG ; 400: KAYNLRSVAV ; YGGGSMWEQA ; KALQEGAEIV ; VCTPGRLIDH ; VKKKATNLQR ; 450: VSYLVFDEAD ; RMFDMGFEYQ ; VRSIASHVRP ; DRQTLLFSAT ; FRKKIEKLAR ; 500: DILIDPIRVV ; QGDIGEANED ; VTQIVEILHS ; GPSKWNWLTR ; RLVEFTSSGS ; 550: VLLFVTKKAN ; AEELASNLKQ ; EGHNLGLLHG ; DMDQSERNKV ; ISDFKKKDIP ; 600: VLVATDVAAR ; GLDIPSIKTV ; INYDVARDID ; THTHRIGRTG ; RAGEKGVAYT ; 650: LLTPKDSNFA ; GDLVRNLEGA ; NQHVSKELLD ; LAMQNAWFRK ; SRFKGGKGKK ; 700: LNIGGGGLGY ; RERPGLGSEN ; SDRGNNNNVM ; SNYEAYKPST ; GAMGDRLTAM ; 750: KAAFQSQYKS ; HFVAASLSNQ ; KAGTSSAGAS ; GWTSAGSLNS ; VPTNSAQQGH ; 800: NSPDNPMTSS ; TKNIPGFNNS ; GNISSAPVTY ; PSIGAQGVNN ; TASGNNSREG ; 850: IGGGNGKRER ; YTENRGGSRH ; SHGDGGNRHG ; DGGRHGDGYR ; YPESGSRHTD ; 900: GHRHGETRHG ; GSAGRHGESR ; GANDGRNGES ; RKEGFNRENK ; MDPKVDSSRM ; 929: DKVDSKTDKT ; PDGFAVPEPP ; KRKKSRWDS
Sequence Length	929
String	Q810A7
Sub Unit	Component of splicing factor SF3B which is composed of at least eight subunits; SF3B1/SAP155/SF3B155, SF3B2/SAP145/SF3B155, SF3B3/SAP130/SF3B130, SF3B4/SAP49/SF3B49, SF3B14A, PHF5A/SF3B14B, SF3B10 and SF3B125. Interacts (via the C-terminus) with TP53BP2; the interaction is not inhibitied by TP53BP2 ubiquitination and is independent of p53/TP53.

Uniprot	Q810A7
Gene Name	Ddx42
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:72047
Unigene	Mm.41367

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803629	E14799m	96T	$776		Add to Cart

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