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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Aprataxin and PNK-like factor

SKU : BHE13801361

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3951m
Alternative Names	Apurinic-apyrimidinic endonuclease APLF
Categories	Elisa
Function	Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.
Specificity	Natural and recombinant Mouse Aprataxin and PNK-like factor
Subcellular Location	Nucleus Cytoplasm cytosol Localizes to DNA damage sites. Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers.
Entryname	APLF_MOUSE
Platform	PF10283
Protein Name	Aprataxin and PNK-like factor
Sequence	50: MPSDFFLQPL ; DGGPRVPVGP ; GQTVIGRGPL ; LGITDKRVSR ; RHAILEVVDS ; 100: QLRIKPIHRN ; PCFYQSSEKS ; QHSPMETQVW ; SQLHPGDSFS ; LLLDKYAFRV ; 150: FSAESEVEME ; CTLRNSQMLD ; EDDILSEMQK ; SPVVNLPDKT ; TGASQLQGSP ; 200: EITKTKCPTI ; DPMSSSGECR ; AFSEHQPRPT ; QRKRILPAWM ; LAESLSDQSL ; 250: STPAEGGDKD ; VIQRSGKAGT ; CEDRTPGNTS ; WHGKKRLSPS ; GNSKSVSAEQ ; 300: DPGKKCRKAD ; QEGPGVSSEN ; VPESSSSNIV ; KDPDVDIVKT ; NKQKDGILIE ; 350: ELGEVSKHKA ; ATKPTTNEEG ; ESCARVQSKS ; PPEKSQGCHP ; ESSSAPSSPD ; 400: ALHTDTADPV ; LGCSEESKVR ; RTACMYGANC ; YRRNPLHFQH ; FSHPGDSDYG ; 450: EVHGTDEGVI ; GDRPECPYGA ; SCYRKNPQHK ; MEYRHSALPA ; RVALDEDDDD ; 499: VGQPSDDEDE ; EDYEPTDEDS ; DWHPGKDDEE ; QEDVDELLKE ; AKSSLHLKH
Sequence Length	499
String	Q9D842
Sub Unit	Interacts with LIG4, PARP1, XRCC1, XRCC4 and XRCC5.

Uniprot	Q9D842
Gene Name	Aplf
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:72103
Unigene	Mm.31770

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801361	E3951m	96T	$776		Add to Cart

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