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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Adiponectin

SKU : BHE13800430

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0605m
Alternative Names	30 kDa adipocyte complement-related protein ; Adipocyte complement-related 30 kDa protein ; ACRP30 ; Adipocyte ; C1q and collagen domain-containing protein ; Adipocyte-specific protein AdipoQ ; Acdc ; Acrp30 ; Apm1
Categories	Elisa
Function	Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Specificity	Natural and recombinant Mouse Adiponectin
Subcellular Location	Secreted
Detection Range	0.156-10ng/mL
Entryname	ADIPO_MOUSE
Method Type	Sandwich
Platform	PF00386
Protein Name	Adiponectin
Sensitivity	0.09ng/mL
Sequence	50: MLLLQALLFL ; LILPSHAEDD ; VTTTEELAPA ; LVPPPKGTCA ; GWMAGIPGHP ; 100: GHNGTPGRDG ; RDGTPGEKGE ; KGDAGLLGPK ; GETGDVGMTG ; AEGPRGFPGT ; 150: PGRKGEPGEA ; AYMYRSAFSV ; GLETRVTVPN ; VPIRFTKIFY ; NQQNHYDGST ; 200: GKFYCNIPGL ; YYFSYHITVY ; MKDVKVSLFK ; KDKAVLFTYD ; QYQEKNVDQA ; 247: SGSVLLHLEV ; GDQVWLQVYG ; DGDHNGLYAD ; NVNDSTFTGF ; LLYHDTN
Sequence Length	247
String	Q60994
Sub Unit	Homomultimer. Forms trimers, hexamers and 12- to 18-mers. The trimers (low molecular weight complexes / LMW) are assembled via non-covalent interactions of the collagen-like domains in a triple helix and hydrophobic interactions within the globular C1q domain. Several trimers can associate to form disulfide-linked hexamers (middle molecular weight complexes / MMW) and larger complexes (higher molecular weight / HMW). The HMW-complex assembly may rely aditionally on lysine hydroxylation and glycosylation. LMW, MMW and HMW complexes bind to HBEGF, MMW and HMW complexes bind to PDGFB, and HMW complex binds to FGF2. Interacts with CTRP9 via the C1q domain (heterotrimeric complex).

Uniprot	Q60994
Gene Name	Adipoq
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:11450
Unigene	Mm.3969

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800430	E0605m	96T	$776		Add to Cart

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