Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
Specificity
Natural and recombinant Human Vitamin K-dependent gamma-carboxylase
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein