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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Vinculin

SKU : BHE13811523

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1839h
Alternative Names	Metavinculin ; MV
Categories	Elisa
Function	Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Specificity	Natural and recombinant Human Vinculin
Subcellular Location	Cytoplasm cytoskeleton Cell junction adherens junction Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II-dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions.
Detection Range	1.56-100ng/mL
Entryname	VINC_HUMAN
Method Type	Sandwich
Platform	PF01044
Protein Name	Vinculin
Sensitivity	0.78ng/mL
Sequence	50: MPVFHTRTIE ; SILEPVAQQI ; SHLVIMHEEG ; EVDGKAIPDL ; TAPVAAVQAA ; 100: VSNLVRVGKE ; TVQTTEDQIL ; KRDMPPAFIK ; VENACTKLVQ ; AAQMLQSDPY ; 150: SVPARDYLID ; GSRGILSGTS ; DLLLTFDEAE ; VRKIIRVCKG ; ILEYLTVAEV ; 200: VETMEDLVTY ; TKNLGPGMTK ; MAKMIDERQQ ; ELTHQEHRVM ; LVNSMNTVKE ; 250: LLPVLISAMK ; IFVTTKNSKN ; QGIEEALKNR ; NFTVEKMSAE ; INEIIRVLQL ; 300: TSWDEDAWAS ; KDTEAMKRAL ; ASIDSKLNQA ; KGWLRDPSAS ; PGDAGEQAIR ; 350: QILDEAGKVG ; ELCAGKERRE ; ILGTCKMLGQ ; MTDQVADLRA ; RGQGSSPVAM ; 400: QKAQQVSQGL ; DVLTAKVENA ; ARKLEAMTNS ; KQSIAKKIDA ; AQNWLADPNG ; 450: GPEGEEQIRG ; ALAEARKIAE ; LCDDPKERDD ; ILRSLGEISA ; LTSKLADLRR ; 500: QGKGDSPEAR ; ALAKQVATAL ; QNLQTKTNRA ; VANSRPAKAA ; VHLEGKIEQA ; 550: QRWIDNPTVD ; DRGVGQAAIR ; GLVAEGHRLA ; NVMMGPYRQD ; LLAKCDRVDQ ; 600: LTAQLADLAA ; RGEGESPQAR ; ALASQLQDSL ; KDLKARMQEA ; MTQEVSDVFS ; 650: DTTTPIKLLA ; VAATAPPDAP ; NREEVFDERA ; ANFENHSGKL ; GATAEKAAAV ; 700: GTANKSTVEG ; IQASVKTARE ; LTPQVVSAAR ; ILLRNPGNQA ; AYEHFETMKN ; 750: QWIDNVEKMT ; GLVDEAIDTK ; SLLDASEEAI ; KKDLDKCKVA ; MANIQPQMLV ; 800: AGATSIARRA ; NRILLVAKRE ; VENSEDPKFR ; EAVKAASDEL ; SKTISPMVMD ; 850: AKAVAGNISD ; PGLQKSFLDS ; GYRILGAVAK ; VREAFQPQEP ; DFPPPPPDLE ; 900: QLRLTDELAP ; PKPPLPEGEV ; PPPRPPPPEE ; KDEEFPEQKA ; GEVINQPMMM ; 950: AARQLHDEAR ; KWSSKPGIPA ; AEVGIGVVAE ; ADAADAAGFP ; VPPDMEDDYE ; 1000: PELLLMPSNQ ; PVNQPILAAA ; QSLHREATKW ; SSKGNDIIAA ; AKRMALLMAE ; 1050: MSRLVRGGSG ; TKRALIQCAK ; DIAKASDEVT ; RLAKEVAKQC ; TDKRIRTNLL ; 1100: QVCERIPTIS ; TQLKILSTVK ; ATMLGRTNIS ; DEESEQATEM ; LVHNAQNLMQ ; 1134: SVKETVREAE ; AASIKIRTDA ; GFTLRWVRKT ; PWYQ
Sequence Length	1134
String	P18206
Sub Unit	Exhibits self-association properties. Interacts with NRAP and SORBS1 (By similarity). Interacts with TLN1. Interacts with SYNM. Interacts with CTNNB1 and this interaction is necessary for its localization to the cell-cell junctions and for its function in regulating cell surface expression of E-cadherin.

Uniprot	P18206
Gene Name	VCL
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7414
Unigene	Hs.643896

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811523	E1839h	96T	$736		Add to Cart

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