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Home / Assay Kits / ELISA Kits

ELISA Kit for Human V-type proton ATPase 116 kDa subunit a isoform 2

SKU : BHE13811448

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E4689h
Alternative Names	Lysosomal H(+)-transporting ATPase V0 subunit a2 ; TJ6 ; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2
Categories	Elisa
Function	Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH.
Specificity	Natural and recombinant Human V-type proton ATPase 116 kDa subunit a isoform 2
Subcellular Location	Cell membrane Multi-pass membrane protein Endosome membrane In kidney proximal tubules, also detected in subapical vesicles.
Detection Range	0.156-10ng/mL
Entryname	VPP2_HUMAN
Method Type	Sandwich
Platform	PF01496
Protein Name	V-type proton ATPase 116 kDa subunit a isoform 2
Sensitivity	0.029ng/mL
Sequence	50: MGSLFRSETM ; CLAQLFLQSG ; TAYECLSALG ; EKGLVQFRDL ; NQNVSSFQRK ; 100: FVGEVKRCEE ; LERILVYLVQ ; EINRADIPLP ; EGEASPPAPP ; LKQVLEMQEQ ; 150: LQKLEVELRE ; VTKNKEKLRK ; NLLELIEYTH ; MLRVTKTFVK ; RNVEFEPTYE ; 200: EFPSLESDSL ; LDYSCMQRLG ; AKLGFVSGLI ; NQGKVEAFEK ; MLWRVCKGYT ; 250: IVSYAELDES ; LEDPETGEVI ; KWYVFLISFW ; GEQIGHKVKK ; ICDCYHCHVY ; 300: PYPNTAEERR ; EIQEGLNTRI ; QDLYTVLHKT ; EDYLRQVLCK ; AAESVYSRVI ; 350: QVKKMKAIYH ; MLNMCSFDVT ; NKCLIAEVWC ; PEADLQDLRR ; ALEEGSRESG ; 400: ATIPSFMNII ; PTKETPPTRI ; RTNKFTEGFQ ; NIVDAYGVGS ; YREVNPALFT ; 450: IITFPFLFAV ; MFGDFGHGFV ; MFLFALLLVL ; NENHPRLNQS ; QEIMRMFFNG ; 500: RYILLLMGLF ; SVYTGLIYND ; CFSKSVNLFG ; SGWNVSAMYS ; SSHPPAEHKK ; 550: MVLWNDSVVR ; HNSILQLDPS ; IPGVFRGPYP ; LGIDPIWNLA ; TNRLTFLNSF ; 600: KMKMSVILGI ; IHMTFGVILG ; IFNHLHFRKK ; FNIYLVSIPE ; LLFMLCIFGY ; 650: LIFMIFYKWL ; VFSAETSRVA ; PSILIEFINM ; FLFPASKTSG ; LYTGQEYVQR ; 700: VLLVVTALSV ; PVLFLGKPLF ; LLWLHNGRSC ; FGVNRSGYTL ; IRKDSEEEVS ; 750: LLGSQDIEEG ; NHQVEDGCRE ; MACEEFNFGE ; ILMTQVIHSI ; EYCLGCISNT ; 800: ASYLRLWALS ; LAHAQLSDVL ; WAMLMRVGLR ; VDTTYGVLLL ; LPVIALFAVL ; 850: TIFILLIMEG ; LSAFLHAIRL ; HWVEFQNKFY ; VGAGTKFVPF ; SFSLLSSKFN ; 856: NDDSVA
Sequence Length	856
String	Q9Y487
Sub Unit	The V-ATPase is an heteromultimeric enzyme composed of at least thirteen different subunits. It has a membrane peripheral V1 sector for ATP hydrolysis and an integral V0 for proton translocation. The V1 sector comprises subunits A-H, whereas V0 includes subunits a, d, c, c', and c''. Directly interacts with PSCD2 through its N-terminal cytosolic tail in an intra-endosomal acidification-dependent manner. Disruption of this interaction results in the inhibition of endocytosis.

Uniprot	Q9Y487
Gene Name	ATP6V0A2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23545
Unigene	Hs.25786

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811448	E4689h	96T	$736		Add to Cart

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