ELISA Kit for Human Ubiquitin-conjugating enzyme E2 A

Mfr.No.	E0991h
Alternative Names	E2 ubiquitin-conjugating enzyme A ; RAD6 homolog A ; HR6A ; Ubiquitin carrier protein A ; Ubiquitin-protein ligase A ; RAD6A
Categories	Elisa
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
Specificity	Natural and recombinant Human Ubiquitin-conjugating enzyme E2 A
Detection Range	0.156-10ng/mL
Entryname	UBE2A_HUMAN
Method Type	Sandwich
Platform	PF00179
Protein Name	Ubiquitin-conjugating enzyme E2 A
Sensitivity	0.078ng/mL
Sequence	50: MSTPARRRLM ; RDFKRLQEDP ; PAGVSGAPSE ; NNIMVWNAVI ; FGPEGTPFED ; 100: GTFKLTIEFT ; EEYPNKPPTV ; RFVSKMFHPN ; VYADGSICLD ; ILQNRWSPTY ; 150: DVSSILTSIQ ; SLLDEPNPNS ; PANSQAAQLY ; QENKREYEKR ; VSAIVEQSWR ; 152: DC
Sequence Length	152
String	P49459
Sub Unit	Interacts with RAD18 and WAC.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811176	E0991h	96T	$736		Add to Cart