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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Tumor necrosis factor receptor superfamily member 6

SKU : BHE13812256

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0030h
Alternative Names	Apo-1 antigen ; Apoptosis-mediating surface antigen FAS ; FASLG receptor ; CD95 ; APT1 ; FAS1 ; TNFRSF6
Categories	Elisa
Function	Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Specificity	Natural and recombinant Human Tumor necrosis factor receptor superfamily member 6
Subcellular Location	Isoform 6 Secreted
Detection Range	78-5000pg/mL
Entryname	TNR6_HUMAN
Method Type	Sandwich
Platform	PF00531
Protein Name	Tumor necrosis factor receptor superfamily member 6
Sensitivity	24pg/mL
Sequence	50: MLGIWTLLPL ; VLTSVARLSS ; KSVNAQVTDI ; NSKGLELRKT ; VTTVETQNLE ; 100: GLHHDGQFCH ; KPCPPGERKA ; RDCTVNGDEP ; DCVPCQEGKE ; YTDKAHFSSK ; 150: CRRCRLCDEG ; HGLEVEINCT ; RTQNTKCRCK ; PNFFCNSTVC ; EHCDPCTKCE ; 200: HGIIKECTLT ; SNTKCKEEGS ; RSNLGWLCLL ; LLPIPLIVWV ; KRKEVQKTCR ; 250: KHRKENQGSH ; ESPTLNPETV ; AINLSDVDLS ; KYITTIAGVM ; TLSQVKGFVR ; 300: KNGVNEAKID ; EIKNDNVQDT ; AEQKVQLLRN ; WHQLHGKKEA ; YDTLIKDLKK ; 335: ANLCTLAEKI ; QTIILKDITS ; DSENSNFRNE ; IQSLV
Sequence Length	335
String	P25445
Sub Unit	Binds DAXX. Interacts with HIPK3. Part of a complex containing HIPK3 and FADD (By similarity). Binds RIPK1 and FAIM2. Interacts with BRE and FEM1B. Interacts with FADD.

Uniprot	P25445
Gene Name	FAS
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:355
Unigene	Hs.244139

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812256	E0030h	96T	$536		Add to Cart

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