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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Toll-like receptor 3

SKU : BHE13811489

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1989h
Alternative Names	CD283
Categories	Elisa
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Specificity	Natural and recombinant Human Toll-like receptor 3
Subcellular Location	Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome membrane
Detection Range	0.156-10ng/mL
Entryname	TLR3_HUMAN
Method Type	Sandwich
Platform	PF00560
Protein Name	Toll-like receptor 3
Sensitivity	0.098ng/mL
Sequence	50: MRQTLPCIYF ; WGGLLPFGML ; CASSTTKCTV ; SHEVADCSHL ; KLTQVPDDLP ; 100: TNITVLNLTH ; NQLRRLPAAN ; FTRYSQLTSL ; DVGFNTISKL ; EPELCQKLPM ; 150: LKVLNLQHNE ; LSQLSDKTFA ; FCTNLTELHL ; MSNSIQKIKN ; NPFVKQKNLI ; 200: TLDLSHNGLS ; STKLGTQVQL ; ENLQELLLSN ; NKIQALKSEE ; LDIFANSSLK ; 250: KLELSSNQIK ; EFSPGCFHAI ; GRLFGLFLNN ; VQLGPSLTEK ; LCLELANTSI ; 300: RNLSLSNSQL ; STTSNTTFLG ; LKWTNLTMLD ; LSYNNLNVVG ; NDSFAWLPQL ; 350: EYFFLEYNNI ; QHLFSHSLHG ; LFNVRYLNLK ; RSFTKQSISL ; ASLPKIDDFS ; 400: FQWLKCLEHL ; NMEDNDIPGI ; KSNMFTGLIN ; LKYLSLSNSF ; TSLRTLTNET ; 450: FVSLAHSPLH ; ILNLTKNKIS ; KIESDAFSWL ; GHLEVLDLGL ; NEIGQELTGQ ; 500: EWRGLENIFE ; IYLSYNKYLQ ; LTRNSFALVP ; SLQRLMLRRV ; ALKNVDSSPS ; 550: PFQPLRNLTI ; LDLSNNNIAN ; INDDMLEGLE ; KLEILDLQHN ; NLARLWKHAN ; 600: PGGPIYFLKG ; LSHLHILNLE ; SNGFDEIPVE ; VFKDLFELKI ; IDLGLNNLNT ; 650: LPASVFNNQV ; SLKSLNLQKN ; LITSVEKKVF ; GPAFRNLTEL ; DMRFNPFDCT ; 700: CESIAWFVNW ; INETHTNIPE ; LSSHYLCNTP ; PHYHGFPVRL ; FDTSSCKDSA ; 750: PFELFFMINT ; SILLIFIFIV ; LLIHFEGWRI ; SFYWNVSVHR ; VLGFKEIDRQ ; 800: TEQFEYAAYI ; IHAYKDKDWV ; WEHFSSMEKE ; DQSLKFCLEE ; RDFEAGVFEL ; 850: EAIVNSIKRS ; RKIIFVITHH ; LLKDPLCKRF ; KVHHAVQQAI ; EQNLDSIILV ; 900: FLEEIPDYKL ; NHALCLRRGM ; FKSHCILNWP ; VQKERIGAFR ; HKLQVALGSK ; 904: NSVH
Sequence Length	904
String	O15455
Sub Unit	Interacts with MYD88 via their respective TIR domains. Interacts (via transmembrane domain) with UNC93B1 (By similarity). Interacts with TICAM1. Homodimer formation is triggered by ligand binding and is required for TLR3 signaling. Binding of double-stranded RNA is required for the interaction with SRC.

Uniprot	O15455
Gene Name	TLR3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7098
Unigene	Hs.657724

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811489	E1989h	96T	$736		Add to Cart

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