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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Tight junction protein ZO-1

SKU : BHE13812009

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9600h
Alternative Names	Tight junction protein 1 ; Zona occludens protein 1 ; Zonula occludens protein 1 ; ZO1
Categories	Elisa
Function	The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Specificity	Natural and recombinant Human Tight junction protein ZO-1
Subcellular Location	Cell membrane Peripheral membrane protein Cytoplasmic side Cell junction tight junction Cell junction Cell junction gap junction Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.
Detection Range	0.312-20ng/mL
Entryname	ZO1_HUMAN
Method Type	Sandwich
Platform	PF00625
Protein Name	Tight junction protein ZO-1
Sensitivity	0.133ng/mL
Sequence	50: MSARAAAAKS ; TAMEETAIWE ; QHTVTLHRAP ; GFGFGIAISG ; GRDNPHFQSG ; 100: ETSIVISDVL ; KGGPAEGQLQ ; ENDRVAMVNG ; VSMDNVEHAF ; AVQQLRKSGK ; 150: NAKITIRRKK ; KVQIPVSRPD ; PEPVSDNEED ; SYDEEIHDPR ; SGRSGVVNRR ; 200: SEKIWPRDRS ; ASRERSLSPR ; SDRRSVASSQ ; PAKPTKVTLV ; KSRKNEEYGL ; 250: RLASHIFVKE ; ISQDSLAARD ; GNIQEGDVVL ; KINGTVTENM ; SLTDAKTLIE ; 300: RSKGKLKMVV ; QRDERATLLN ; VPDLSDSIHS ; ANASERDDIS ; EIQSLASDHS ; 350: GRSHDRPPRR ; SRSRSPDQRS ; EPSDHSRHSP ; QQPSNGSLRS ; RDEERISKPG ; 400: AVSTPVKHAD ; DHTPKTVEEV ; TVERNEKQTP ; SLPEPKPVYA ; QVGQPDVDLP ; 450: VSPSDGVLPN ; STHEDGILRP ; SMKLVKFRKG ; DSVGLRLAGG ; NDVGIFVAGV ; 500: LEDSPAAKEG ; LEEGDQILRV ; NNVDFTNIIR ; EEAVLFLLDL ; PKGEEVTILA ; 550: QKKKDVYRRI ; VESDVGDSFY ; IRTHFEYEKE ; SPYGLSFNKG ; EVFRVVDTLY ; 600: NGKLGSWLAI ; RIGKNHKEVE ; RGIIPNKNRA ; EQLASVQYTL ; PKTAGGDRAD ; 650: FWRFRGLRSS ; KRNLRKSRED ; LSAQPVQTKF ; PAYERVVLRE ; AGFLRPVTIF ; 700: GPIADVAREK ; LAREEPDIYQ ; IAKSEPRDAG ; TDQRSSGIIR ; LHTIKQIIDQ ; 750: DKHALLDVTP ; NAVDRLNYAQ ; WYPIVVFLNP ; DSKQGVKTMR ; MRLCPESRKS ; 800: ARKLYERSHK ; LRKNNHHLFT ; TTINLNSMND ; GWYGALKEAI ; QQQQNQLVWV ; 850: SEGKADGATS ; DDLDLHDDRL ; SYLSAPGSEY ; SMYSTDSRHT ; SDYEDTDTEG ; 900: GAYTDQELDE ; TLNDEVGTPP ; ESAITRSSEP ; VREDSSGMHH ; ENQTYPPYSP ; 950: QAQPQPIHRI ; DSPGFKPASQ ; QKAEASSPVP ; YLSPETNPAS ; STSAVNHNVN ; 1000: LTNVRLEEPT ; PAPSTSYSPQ ; ADSLRTPSTE ; AAHIMLRDQE ; PSLSSHVDPT ; 1050: KVYRKDPYPE ; EMMRQNHVLK ; QPAVSHPGHR ; PDKEPNLTYE ; PQLPYVEKQA ; 1100: SRDLEQPTYR ; YESSSYTDQF ; SRNYEHRLRY ; EDRVPMYEEQ ; WSYYDDKQPY ; 1150: PSRPPFDNQH ; SQDLDSRQHP ; EESSERGYFP ; RFEEPAPLSY ; DSRPRYEQAP ; 1200: RASALRHEEQ ; PAPGYDTHGR ; LRPEAQPHPS ; AGPKPAESKQ ; YFEQYSRSYE ; 1250: QVPPQGFTSR ; AGHFEPLHGA ; AAVPPLIPSS ; QHKPEALPSN ; TKPLPPPPTQ ; 1300: TEEEEDPAMK ; PQSVLTRVKM ; FENKRSASLE ; TKKDVNDTGS ; FKPPEVASKP ; 1350: SGAPIIGPKP ; TSQNQFSEHD ; KTLYRIPEPQ ; KPQLKPPEDI ; VRSNHYDPEE ; 1400: DEEYYRKQLS ; YFDRRSFENK ; PPAHIAASHL ; SEPAKPAHSQ ; NQSNFSSYSS ; 1450: KGKPPEADGV ; DRSFGEKRYE ; PIQATPPPPP ; LPSQYAQPSQ ; PVTSASLHIH ; 1500: SKGAHGEGNS ; VSLDFQNSLV ; SKPDPPPSQN ; KPATFRPPNR ; EDTAQAAFYP ; 1550: QKSFPDKAPV ; NGTEQTQKTV ; TPAYNRFTPK ; PYTSSARPFE ; RKFESPKFNH ; 1600: NLLPSETAHK ; PDLSSKTPTS ; PKTLVKSHSL ; AQPPEFDSGV ; ETFSIHAEKP ; 1650: KYQINNISTV ; PKAIPVSPSA ; VEEDEDEDGH ; TVVATARGIF ; NSNGGVLSSI ; 1700: ETGVSIIIPQ ; GAIPEGVEQE ; IYFKVCRDNS ; ILPPLDKEKG ; ETLLSPLVMC ; 1748: GPHGLKFLKP ; VELRLPHCDP ; KTWQNKCLPG ; DPNYLVGANC ; VSVLIDHF
Sequence Length	1748
String	Q07157
Sub Unit	Interacts with BVES (via the C-terminus cytoplasmic tail). Interacts with HSPA4 and KIRREL1 (By similarity). Homodimer, and heterodimer with TJP2/ZO-2 and TJP3/ZO-3. Interacts with OCLN, CALM, claudins, CGN/cingulin, CXADR, GJA12, GJD3 and UBN1. Interacts (via ZU5 domain) with CDC42BPB and GCOM1. Interacts (via PDZ domain) with GJA1.

Uniprot	Q07157
Gene Name	TJP1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7082
Unigene	Hs.743990

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SKU	Supplier No.	Size	Your price	Quantity
BHE13812009	E9600h	96T	$736		Add to Cart

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