Antioxidant protein 1 ; AOP-1 ; HBC189 ; Peroxiredoxin III ; Prx-III ; Peroxiredoxin-3 ; Protein MER5 homolog ; AOP1
Categories
Elisa
Function
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Specificity
Natural and recombinant Human Thioredoxin-dependent peroxide reductase, mitochondrial
Dodecameric ring assembled from homodimeric units; disulfide-linked, upon oxidation. The rings have an approximate diameter of 150 A and a central hole of 70 A. 3-5% of the rings are interlocked by pairs. Binds MAP3K13. Interacts with NEK6.