JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human TAR DNA-binding protein 43

SKU : BHE13810764

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E1951h
Alternative Names	TDP43
Categories	Elisa
Function	DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
Specificity	Natural and recombinant Human TAR DNA-binding protein 43
Subcellular Location	Nucleus In patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis, it is absent from the nucleus of affected neurons but it is the primary component of cytoplasmic ubiquitin-positive inclusion bodies.
Detection Range	0.312-20ng/mL
Entryname	TADBP_HUMAN
Method Type	Sandwich
Platform	PF00076
Protein Name	TAR DNA-binding protein 43
Sensitivity	0.137 ng/mL
Sequence	50: MSEYIRVTED ; ENDEPIEIPS ; EDDGTVLLST ; VTAQFPGACG ; LRYRNPVSQC ; 100: MRGVRLVEGI ; LHAPDAGWGN ; LVYVVNYPKD ; NKRKMDETDA ; SSAVKVKRAV ; 150: QKTSDLIVLG ; LPWKTTEQDL ; KEYFSTFGEV ; LMVQVKKDLK ; TGHSKGFGFV ; 200: RFTEYETQVK ; VMSQRHMIDG ; RWCDCKLPNS ; KQSQDEPLRS ; RKVFVGRCTE ; 250: DMTEDELREF ; FSQYGDVMDV ; FIPKPFRAFA ; FVTFADDQIA ; QSLCGEDLII ; 300: KGISVHISNA ; EPKHNSNRQL ; ERSGRFGGNP ; GGFGNQGGFG ; NSRGGGAGLG ; 350: NNQGSNMGGG ; MNFGAFSINP ; AMMAAAQAAL ; QSSWGMMGML ; ASQQNQSGPS ; 400: GNNQNQGNMQ ; REPNQAFGSG ; NNSYSGSNSG ; AAIGWGSASN ; AGSGSGFNGG ; 414: FGSSMDSKSS ; GWGM
Sequence Length	414
String	Q13148
Sub Unit	Homodimer (By similarity). Binds specifically to pyrimidine-rich motifs of TAR DNA and to single stranded TG repeated sequences. Binds to RNA, specifically to UG repeated sequences with a minimun of six contiguous repeats. Interacts with ATNX2; the interaction is RNA-dependent.

Uniprot	Q13148
Gene Name	TARDBP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23435
Unigene	Hs.300624

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13810764	E1951h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.