Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins. In fibroblasts, it may have tumor-suppressing capabilities being involved in growth regulation.
Specificity
Natural and recombinant Human Sulfhydryl oxidase 1
Subcellular Location
Isoform 2 Secreted extracellular space Found in the extracellular medium of quiescent cells but is not found in proliferating cells.