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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Structural maintenance of chromosomes protein 4

SKU : BHE13810358

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3349h
Alternative Names	Chromosome-associated polypeptide C ; hCAP-C ; XCAP-C homolog ; CAPC ; SMC4L1
Categories	Elisa
Function	Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Specificity	Natural and recombinant Human Structural maintenance of chromosomes protein 4
Subcellular Location	Nucleus Cytoplasm Chromosome In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Detection Range	78-5000pg/mL
Entryname	SMC4_HUMAN
Method Type	Sandwich
Platform	PF06470
Protein Name	Structural maintenance of chromosomes protein 4
Sensitivity	32pg/ml
Sequence	50: MPRKGTQPST ; ARRREEGPPP ; PSPDGASSDA ; EPEPPSGRTE ; SPATAAETAS ; 100: EELDNRSLEE ; ILNSIPPPPP ; PAMTNEAGAP ; RLMITHIVNQ ; NFKSYAGEKI ; 150: LGPFHKRFSC ; IIGPNGSGKS ; NVIDSMLFVF ; GYRAQKIRSK ; KLSVLIHNSD ; 200: EHKDIQSCTV ; EVHFQKIIDK ; EGDDYEVIPN ; SNFYVSRTAC ; RDNTSVYHIS ; 250: GKKKTFKDVG ; NLLRSHGIDL ; DHNRFLILQG ; EVEQIAMMKP ; KGQTEHDEGM ; 300: LEYLEDIIGC ; GRLNEPIKVL ; CRRVEILNEH ; RGEKLNRVKM ; VEKEKDALEG ; 350: EKNIAIEFLT ; LENEIFRKKN ; HVCQYYIYEL ; QKRIAEMETQ ; KEKIHEDTKE ; 400: INEKSNILSN ; EMKAKNKDVK ; DTEKKLNKIT ; KFIEENKEKF ; TQLDLEDVQV ; 450: REKLKHATSK ; AKKLEKQLQK ; DKEKVEEFKS ; IPAKSNNIIN ; ETTTRNNALE ; 500: KEKEKEEKKL ; KEVMDSLKQE ; TQGLQKEKES ; REKELMGFSK ; SVNEARSKMD ; 550: VAQSELDIYL ; SRHNTAVSQL ; TKAKEALIAA ; SETLKERKAA ; IRDIEGKLPQ ; 600: TEQELKEKEK ; ELQKLTQEET ; NFKSLVHDLF ; QKVEEAKSSL ; AMNRSRGKVL ; 650: DAIIQEKKSG ; RIPGIYGRLG ; DLGAIDEKYD ; VAISSCCHAL ; DYIVVDSIDI ; 700: AQECVNFLKR ; QNIGVATFIG ; LDKMAVWAKK ; MTEIQTPENT ; PRLFDLVKVK ; 750: DEKIRQAFYF ; ALRDTLVADN ; LDQATRVAYQ ; KDRRWRVVTL ; QGQIIEQSGT ; 800: MTGGGSKVMK ; GRMGSSLVIE ; ISEEEVNKME ; SQLQNDSKKA ; MQIQEQKVQL ; 850: EERVVKLRHS ; EREMRNTLEK ; FTASIQRLIE ; QEEYLNVQVK ; ELEANVLATA ; 900: PDKKKQKLLE ; ENVSAFKTEY ; DAVAEKAGKV ; EAEVKRLHNT ; IVEINNHKLK ; 950: AQQDKLDKIN ; KQLDECASAI ; TKAQVAIKTA ; DRNLQKAQDS ; VLRTEKEIKD ; 1000: TEKEVDDLTA ; ELKSLEDKAA ; EVVKNTNAAE ; ESLPEIQKEH ; RNLLQELKVI ; 1050: QENEHALQKD ; ALSIKLKLEQ ; IDGHIAEHNS ; KIKYWHKEIS ; KISLHPIEDN ; 1100: PIEEISVLSP ; EDLEAIKNPD ; SITNQIALLE ; ARCHEMKPNL ; GAIAEYKKKE ; 1150: ELYLQRVAEL ; DKITYERDSF ; RQAYEDLRKQ ; RLNEFMAGFY ; IITNKLKENY ; 1200: QMLTLGGDAE ; LELVDSLDPF ; SEGIMFSVRP ; PKKSWKKIFN ; LSGGEKTLSS ; 1250: LALVFALHHY ; KPTPLYFMDE ; IDAALDFKNV ; SIVAFYIYEQ ; TKNAQFIIIS ; 1288: LRNNMFEISD ; RLIGIYKTYN ; ITKSVAVNPK ; EIASKGLC
Sequence Length	1288
String	Q9NTJ3
Sub Unit	Forms an heterodimer with SMC2. Component of the condensin complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits that probably regulate the complex: BRRN1/CAPH, CNAP1/CAPD2 and CAPG.

Uniprot	Q9NTJ3
Gene Name	SMC4
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10051
Unigene	Hs.58992

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810358	E3349h	96T	$736		Add to Cart

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