JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Sterol regulatory element-binding protein 2

SKU : BHE13810356

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E12196h
Alternative Names	Class D basic helix-loop-helix protein 2 ; bHLHd2 ; Sterol regulatory element-binding transcription factor 2 ; BHLHD2 ; SREBP2
Categories	Elisa
Function	Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity). Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Specificity	Natural and recombinant Human Sterol regulatory element-binding protein 2
Subcellular Location	Processed sterol regulatory element-binding protein 2 Nucleus
Detection Range	0.312-20ng/mL
Entryname	SRBP2_HUMAN
Method Type	Sandwich
Platform	PF00010
Protein Name	Sterol regulatory element-binding protein 2
Sensitivity	0.12ng/ml
Sequence	50: MDDSGELGGL ; ETMETLTELG ; DELTLGDIDE ; MLQFVSNQVG ; EFPDLFSEQL ; 100: CSSFPGSGGS ; GSSSGSSGSS ; SSSSNGRGSS ; SGAVDPSVQR ; SFTQVTLPSF ; 150: SPSAASPQAP ; TLQVKVSPTS ; VPTTPRATPI ; LQPRPQPQPQ ; PQTQLQQQTV ; 200: MITPTFSTTP ; QTRIIQQPLI ; YQNAATSFQV ; LQPQVQSLVT ; SSQVQPVTIQ ; 250: QQVQTVQAQR ; VLTQTANGTL ; QTLAPATVQT ; VAAPQVQQVP ; VLVQPQIIKT ; 300: DSLVLTTLKT ; DGSPVMAAVQ ; NPALTALTTP ; IQTAALQVPT ; LVGSSGTILT ; 350: TMPVMMGQEK ; VPIKQVPGGV ; KQLEPPKEGE ; RRTTHNIIEK ; RYRSSINDKI ; 400: IELKDLVMGT ; DAKMHKSGVL ; RKAIDYIKYL ; QQVNHKLRQE ; NMVLKLANQK ; 450: NKLLKGIDLG ; SLVDNEVDLK ; IEDFNQNVLL ; MSPPASDSGS ; QAGFSPYSID ; 500: SEPGSPLLDD ; AKVKDEPDSP ; PVALGMVDRS ; RILLCVLTFL ; CLSFNPLTSL ; 550: LQWGGAHDSD ; QHPHSGSGRS ; VLSFESGSGG ; WFDWMMPTLL ; LWLVNGVIVL ; 600: SVFVKLLVHG ; EPVIRPHSRS ; SVTFWRHRKQ ; ADLDLARGDF ; AAAAGNLQTC ; 650: LAVLGRALPT ; SRLDLACSLS ; WNVIRYSLQK ; LRLVRWLLKK ; VFQCRRATPA ; 700: TEAGFEDEAK ; TSARDAALAY ; HRLHQLHITG ; KLPAGSACSD ; VHMALCAVNL ; 750: AECAEEKIPP ; STLVEIHLTA ; AMGLKTRCGG ; KLGFLASYFL ; SRAQSLCGPE ; 800: HSAVPDSLRW ; LCHPLGQKFF ; MERSWSVKSA ; AKESLYCAQR ; NPADPIAQVH ; 850: QAFCKNLLER ; AIESLVKPQA ; KKKAGDQEEE ; SCEFSSALEY ; LKLLHSFVDS ; 900: VGVMSPPLSR ; SSVLKSALGP ; DIICRWWTSA ; ITVAISWLQG ; DDAAVRSHFT ; 950: KVERIPKALE ; VTESPLVKAI ; FHACRAMHAS ; LPGKADGQQS ; SFCHCERASG ; 1000: HLWSSLNVSG ; ATSDPALNHV ; VQLLTCDLLL ; SLRTALWQKQ ; ASASQAVGET ; 1050: YHASGAELAG ; FQRDLGSLRR ; LAHSFRPAYR ; KVFLHEATVR ; LMAGASPTRT ; 1100: HQLLEHSLRR ; RTTQSTKHGE ; VDAWPGQRER ; ATAILLACRH ; LPLSFLSSPG ; 1141: QRAVLLAEAA ; RTLEKVGDRR ; SCNDCQQMIV ; KLGGGTAIAA ; S
Sequence Length	1141
String	Q12772
Sub Unit	Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. Component of SCAP/SREBP complex composed of SREBF2, SCAP and RNF139; the complex hampers the interaction between SCAP and SEC24B, thereby reducing SREBF2 proteolytic processing. Interacts (via C-terminus domain) with RNF139.

Uniprot	Q12772
Gene Name	SREBF2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6721
Unigene	Hs.443258

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13810356	E12196h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.