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Home / Assay Kits / ELISA Kits

ELISA Kit for Human STAM-binding protein

SKU : BHE13810625

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E13104h
Alternative Names	Associated molecule with the SH3 domain of STAM ; Endosome-associated ubiquitin isopeptidase ; AMSH
Categories	Elisa
Function	Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Functions at the endosome and is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7.
Specificity	Natural and recombinant Human STAM-binding protein
Subcellular Location	Nucleus Membrane Peripheral membrane protein Cytoplasm Early endosome
Entryname	STABP_HUMAN
Platform	PF01398
Protein Name	STAM-binding protein
Sequence	50: MSDHGDVSLP ; PEDRVRALSQ ; LGSAVEVNED ; IPPRRYFRSG ; VEIIRMASIY ; 100: SEEGNIEHAF ; ILYNKYITLF ; IEKLPKHRDY ; KSAVIPEKKD ; TVKKLKEIAF ; 150: PKAEELKAEL ; LKRYTKEYTE ; YNEEKKKEAE ; ELARNMAIQQ ; ELEKEKQRVA ; 200: QQKQQQLEQE ; QFHAFEEMIR ; NQELEKERLK ; IVQEFGKVDP ; GLGGPLVPDL ; 250: EKPSLDVFPT ; LTVSSIQPSD ; CHTTVRPAKP ; PVVDRSLKPG ; ALSNSESIPT ; 300: IDGLRHVVVP ; GRLCPQFLQL ; ASANTARGVE ; TCGILCGKLM ; RNEFTITHVL ; 350: IPKQSAGSDY ; CNTENEEELF ; LIQDQQGLIT ; LGWIHTHPTQ ; TAFLSSVDLH ; 400: THCSYQMMLP ; ESVAIVCSPK ; FQETGFFKLT ; DHGLEEISSC ; RQKGFHPHSK ; 424: DPPLFCSCSH ; VTVVDRAVTI ; TDLR
Sequence Length	424
String	O95630
Sub Unit	Interacts with STAM1. Interacts with SMAD6 and SMAD7. Interacts with CHMP3; the interaction appears to relieve the autoinhibition of CHMP3. Interacts with SMURF2 and RNF11; this interaction promotes ubiquitination.

Uniprot	O95630
Gene Name	STAMBP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10617
Unigene	Hs.469018

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810625	E13104h	96T	$736		Add to Cart

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