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ELISA Kit for Human Stabilin-2

SKU : BHE13810411

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0466h
Alternative Names	FAS1 EGF-like and X-link domain-containing adhesion molecule 2 ; Fasciclin ; EGF-like ; laminin-type EGF-like and link domain-containing scavenger receptor 2 ; FEEL-2 ; Hyaluronan receptor for endocytosis ; FEEL2 ; FELL ; FEX2 ; HARE
Categories	Elisa
Function	Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalisation as well as HA and CS.
Specificity	Natural and recombinant Human Stabilin-2
Subcellular Location	Cell membrane Single-pass type I membrane protein Cytoplasm Only a small amount appears to be present at the cell surface.
Detection Range	78-5000pg/mL
Entryname	STAB2_HUMAN
Method Type	Sandwich
Platform	PF12947
Protein Name	Stabilin-2
Sensitivity	39.1pg/mL
Sequence	50: MMLQHLVIFC ; LGLVVQNFCS ; PAETTGQARR ; CDRKSLLTIR ; TECRSCALNL ; 100: GVKCPDGYTM ; ITSGSVGVRD ; CRYTFEVRTY ; SLSLPGCRHI ; CRKDYLQPRC ; 150: CPGRWGPDCI ; ECPGGAGSPC ; NGRGSCAEGM ; EGNGTCSCQE ; GFGGTACETC ; 200: ADDNLFGPSC ; SSVCNCVHGV ; CNSGLDGDGT ; CECYSAYTGP ; KCDKPIPECA ; 250: ALLCPENSRC ; SPSTEDENKL ; ECKCLPNYRG ; DGKYCDPINP ; CLRKICHPHA ; 300: HCTYLGPNRH ; SCTCQEGYRG ; DGQVCLPVDP ; CQINFGNCPT ; KSTVCKYDGP ; 350: GQSHCECKEH ; YQNFVPGVGC ; SMTDICKSDN ; PCHRNANCTT ; VAPGRTECIC ; 400: QKGYVGDGLT ; CYGNIMERLR ; ELNTEPRGKW ; QGRLTSFISL ; LDKAYAWPLS ; 450: KLGPFTVLLP ; TDKGLKGFNV ; NELLVDNKAA ; QYFVKLHIIA ; GQMNIEYMNN ; 500: TDMFYTLTGK ; SGEIFNSDKD ; NQIKLKLHGG ; KKKVKIIQGD ; IIASNGLLHI ; 550: LDRAMDKLEP ; TFESNNEQTI ; MTMLQPRYSK ; FRSLLEETNL ; GHALDEDGVG ; 600: GPYTIFVPNN ; EALNNMKDGT ; LDYLLSPEGS ; RKLLELVRYH ; IVPFTQLEVA ; 650: TLISTPHIRS ; MANQLIQFNT ; TDNGQILAND ; VAMEEIEITA ; KNGRIYTLTG ; 700: VLIPPSIVPI ; LPHRCDETKR ; EMKLGTCVSC ; SLVYWSRCPA ; NSEPTALFTH ; 750: RCVYSGRFGS ; LKSGCARYCN ; ATVKIPKCCK ; GFYGPDCNQC ; PGGFSNPCSG ; 800: NGQCADSLGG ; NGTCICEEGF ; QGSQCQFCSD ; PNKYGPRCNK ; KCLCVHGTCN ; 850: NRIDSDGACL ; TGTCRDGSAG ; RLCDKQTSAC ; GPYVQFCHIH ; ATCEYSNGTA ; 900: SCICKAGYEG ; DGTLCSEMDP ; CTGLTPGGCS ; RNAECIKTGT ; GTHTCVCQQG ; 950: WTGNGRDCSE ; INNCLLPSAG ; GCHDNASCLY ; VGPGQNECEC ; KKGFRGNGID ; 1000: CEPITSCLEQ ; TGKCHPLASC ; QSTSSGVWSC ; VCQEGYEGDG ; FLCYGNAAVE ; 1050: LSFLSEAAIF ; NRWINNASLQ ; PTLSATSNLT ; VLVPSQQATE ; DMDQDEKSFW ; 1100: LSQSNIPALI ; KYHMLLGTYR ; VADLQTLSSS ; DMLATSLQGN ; FLHLAKVDGN ; 1150: ITIEGASIVD ; GDNAATNGVI ; HIINKVLVPQ ; RRLTGSLPNL ; LMRLEQMPDY ; 1200: SIFRGYIIQY ; NLANAIEAAD ; AYTVFAPNNN ; AIENYIREKK ; VLSLEEDVLR ; 1250: YHVVLEEKLL ; KNDLHNGMHR ; ETMLGFSYFL ; SFFLHNDQLY ; VNEAPINYTN ; 1300: VATDKGVIHG ; LGKVLEIQKN ; RCDNNDTTII ; RGRCRTCSSE ; LTCPFGTKSL ; 1350: GNEKRRCIYT ; SYFMGRRTLF ; IGCQPKCVRT ; VITRECCAGF ; FGPQCQPCPG ; 1400: NAQNVCFGNG ; ICLDGVNGTG ; VCECGEGFSG ; TACETCTEGK ; YGIHCDQACS ; 1450: CVHGRCNQGP ; LGDGSCDCDV ; GWRGVHCDNA ; TTEDNCNGTC ; HTSANCLTNS ; 1500: DGTASCKCAA ; GFQGNGTICT ; AINACEISNG ; GCSAKADCKR ; TTPGRRVCTC ; 1550: KAGYTGDGIV ; CLEINPCLEN ; HGGCDKNAEC ; TQTGPNQAAC ; NCLPAYTGDG ; 1600: KVCTLINVCL ; TKNGGCSEFA ; ICNHTGQVER ; TCTCKPNYIG ; DGFTCRGSIY ; 1650: QELPKNPKTS ; QYFFQLQEHF ; VKDLVGPGPF ; TVFAPLSAAF ; DEEARVKDWD ; 1700: KYGLMPQVLR ; YHVVACHQLL ; LENLKLISNA ; TSLQGEPIVI ; SVSQSTVYIN ; 1750: NKAKIISSDI ; ISTNGIVHII ; DKLLSPKNLL ; ITPKDNSGRI ; LQNLTTLATN ; 1800: NGYIKFSNLI ; QDSGLLSVIT ; DPIHTPVTLF ; WPTDQALHAL ; PAEQQDFLFN ; 1850: QDNKDKLKEY ; LKFHVIRDAK ; VLAVDLPTST ; AWKTLQGSEL ; SVKCGAGRDI ; 1900: GDLFLNGQTC ; RIVQRELLFD ; LGVAYGIDCL ; LIDPTLGGRC ; DTFTTFDASG ; 1950: ECGSCVNTPS ; CPRWSKPKGV ; KQKCLYNLPF ; KRNLEGCRER ; CSLVIQIPRC ; 2000: CKGYFGRDCQ ; ACPGGPDAPC ; NNRGVCLDQY ; SATGECKCNT ; GFNGTACEMC ; 2050: WPGRFGPDCL ; PCGCSDHGQC ; DDGITGSGQC ; LCETGWTGPS ; CDTQAVLPAV ; 2100: CTPPCSAHAT ; CKENNTCECN ; LDYEGDGITC ; TVVDFCKQDN ; GGCAKVARCS ; 2150: QKGTKVSCSC ; QKGYKGDGHS ; CTEIDPCADG ; LNGGCHEHAT ; CKMTGPGKHK ; 2200: CECKSHYVGD ; GLNCEPEQLP ; IDRCLQDNGQ ; CHADAKCVDL ; HFQDTTVGVF ; 2250: HLRSPLGQYK ; LTFDKAREAC ; ANEAATMATY ; NQLSYAQKAK ; YHLCSAGWLE ; 2300: TGRVAYPTAF ; ASQNCGSGVV ; GIVDYGPRPN ; KSEMWDVFCY ; RMKDVNCTCK ; 2350: VGYVGDGFSC ; SGNLLQVLMS ; FPSLTNFLTE ; VLAYSNSSAR ; GRAFLEHLTD ; 2400: LSIRGTLFVP ; QNSGLGENET ; LSGRDIEHHL ; ANVSMFFYND ; LVNGTTLQTR ; 2450: LGSKLLITAS ; QDPLQPTETR ; FVDGRAILQW ; DIFASNGIIH ; VISRPLKAPP ; 2500: APVTLTHTGL ; GAGIFFAIIL ; VTGAVALAAY ; SYFRINRRTI ; GFQHFESEED ; 2550: INVAALGKQQ ; PENISNPLYE ; STTSAPPEPS ; YDPFTDSEER ; QLEGNDPLRT ; 2551: L
Sequence Length	2551
String	Q8WWQ8
Sub Unit	Interacts with GULP1 and heparin. Also interacts with alpha-M/beta-2 integrin (ITGAM and ITGB2) and thymosin beta 4 (TMSB4X and/or TMSB4Y).

Uniprot	Q8WWQ8
Gene Name	STAB2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:55576
Unigene	Hs.408249

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