JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Spastin

SKU : BHE13810469

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E15329h
Alternative Names	Spastic paraplegia 4 protein ; ADPSP ; FSP2 ; KIAA1083 ; SPG4
Categories	Elisa
Function	ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. May also play a role in axon growth and the formation of axonal branches.
Specificity	Natural and recombinant Human Spastin
Subcellular Location	Membrane Single-pass membrane protein Cytoplasm cytoskeleton centrosome Cytoplasm cytoskeleton Cytoplasm perinuclear region Endoplasmic reticulum Endosome Nucleus Cytoplasm cytoskeleton spindle Localization to the centrosome is independent of microtubules. Localizes to the midbody of dividing cells, and this requires CHMP1B. Enriched in the distal axons and branches of postmitotic neurons. Isoform 3 is the main endosomal form.
Detection Range	0.312-20ng/mL
Entryname	SPAST_HUMAN
Method Type	Sandwich
Platform	PF00004
Protein Name	Spastin
Sensitivity	0.093 ng/mL
Sequence	50: MNSPGGRGKK ; KGSGGASNPV ; PPRPPPPCLA ; PAPPAAGPAP ; PPESPHKRNL ; 100: YYFSYPLFVG ; FALLRLVAFH ; LGLLFVWLCQ ; RFSRALMAAK ; RSSGAAPAPA ; 150: SASAPAPVPG ; GEAERVRVFH ; KQAFEYISIA ; LRIDEDEKAG ; QKEQAVEWYK ; 200: KGIEELEKGI ; AVIVTGQGEQ ; CERARRLQAK ; MMTNLVMAKD ; RLQLLEKMQP ; 250: VLPFSKSQTD ; VYNDSTNLAC ; RNGHLQSESG ; AVPKRKDPLT ; HTSNSLPRSK ; 300: TVMKTGSAGL ; SGHHRAPSYS ; GLSMVSGVKQ ; GSGPAPTTHK ; GTPKTNRTNK ; 350: PSTPTTATRK ; KKDLKNFRNV ; DSNLANLIMN ; EIVDNGTAVK ; FDDIAGQDLA ; 400: KQALQEIVIL ; PSLRPELFTG ; LRAPARGLLL ; FGPPGNGKTM ; LAKAVAAESN ; 450: ATFFNISAAS ; LTSKYVGEGE ; KLVRALFAVA ; RELQPSIIFI ; DEVDSLLCER ; 500: REGEHDASRR ; LKTEFLIEFD ; GVQSAGDDRV ; LVMGATNRPQ ; ELDEAVLRRF ; 550: IKRVYVSLPN ; EETRLLLLKN ; LLCKQGSPLT ; QKELAQLARM ; TDGYSGSDLT ; 600: ALAKDAALGP ; IRELKPEQVK ; NMSASEMRNI ; RLSDFTESLK ; KIKRSVSPQT ; 616: LEAYIRWNKD ; FGDTTV
Sequence Length	616
String	Q9UBP0
Sub Unit	Homohexamer. Binding to ATP stabilizes the homohexameric form. Binds to microtubules at least in part via the alpha-tubulin and beta-tubulin tails. The hexamer may adopt a ring conformation through which microtubules pass prior to being severed. Does not interact strongly with tubulin heterodimers. Interacts (via MIT domain) with CHMP1B; the interaction is direct. Interacts with ATL1, RTN1, SSNA1 and ZFYVE27.

Uniprot	Q9UBP0
Gene Name	SPAST
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:6683
Unigene	Hs.468091

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13810469	E15329h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.