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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Serine/threonine-protein phosphatase 2A activator

SKU : BHE13808747

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10699h
Alternative Names	PP2A ; subunit B' ; PR53 isoform ; Phosphotyrosyl phosphatase activator ; PTPA ; Serine/threonine-protein phosphatase 2A regulatory subunit 4 ; Serine/threonine-protein phosphatase 2A regulatory subunit B' ; PTPA
Categories	Elisa
Function	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activty of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
Specificity	Natural and recombinant Human Serine/threonine-protein phosphatase 2A activator
Subcellular Location	Cytoplasm Nucleus
Detection Range	78-5000pg/mL
Entryname	PTPA_HUMAN
Method Type	Sandwich
Platform	PF03095
Protein Name	Serine/threonine-protein phosphatase 2A activator
Sensitivity	40.3pg/mL
Sequence	50: MAEGERQPPP ; DSSEEAPPAT ; QNFIIPKKEI ; HTVPDMGKWK ; RSQAYADYIG ; 100: FILTLNEGVK ; GKKLTFEYRV ; SEMWNEVHEE ; KEQAAKQSVS ; CDECIPLPRA ; 150: GHCAPSEAIE ; KLVALLNTLD ; RWIDETPPVD ; QPSRFGNKAY ; RTWYAKLDEE ; 200: AENLVATVVP ; THLAAAVPEV ; AVYLKESVGN ; STRIDYGTGH ; EAAFAAFLCC ; 250: LCKIGVLRVD ; DQIAIVFKVF ; NRYLEVMRKL ; QKTYRMEPAG ; SQGVWGLDDF ; 300: QFLPFIWGSS ; QLIDHPYLEP ; RHFVDEKAVN ; ENHKDYMFLE ; CILFITEMKT ; 350: GPFAEHSNQL ; WNISAVPSWS ; KVNQGLIRMY ; KAECLEKFPV ; IQHFKFGSLL ; 358: PIHPVTSG
Sequence Length	358
String	Q15257
Sub Unit	Associates with PP2A heterodimeric core enzyme PP2A(D), composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A). Interacts with PPP2CB.

Uniprot	Q15257
Gene Name	PPP2R4
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5524
Unigene	Hs.400740

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808747	E10699h	96T	$736		Add to Cart

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