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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Serine/threonine-protein kinase TAO1

SKU : BHE13810107

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2238h
Alternative Names	Kinase from chicken homolog B ; hKFC-B ; MARK Kinase ; MARKK ; Prostate-derived sterile 20-like kinase 2 ; PSK-2 ; Thousand and one amino acid protein kinase 1 ; TAOK1 ; KIAA1361 ; MAP3K16 ; MARKK
Categories	Elisa
Function	Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.
Specificity	Natural and recombinant Human Serine/threonine-protein kinase TAO1
Subcellular Location	Cytoplasm
Detection Range	78-5000pg/ml
Entryname	TAOK1_HUMAN
Method Type	Sandwich
Platform	PF00069
Protein Name	Serine/threonine-protein kinase TAO1
Sensitivity	39pg/mL
Sequence	50: MPSTNRAGSL ; KDPEIAELFF ; KEDPEKLFTD ; LREIGHGSFG ; AVYFARDVRT ; 100: NEVVAIKKMS ; YSGKQSTEKW ; QDIIKEVKFL ; QRIKHPNSIE ; YKGCYLREHT ; 150: AWLVMEYCLG ; SASDLLEVHK ; KPLQEVEIAA ; ITHGALQGLA ; YLHSHTMIHR ; 200: DIKAGNILLT ; EPGQVKLADF ; GSASMASPAN ; SFVGTPYWMA ; PEVILAMDEG ; 250: QYDGKVDVWS ; LGITCIELAE ; RKPPLFNMNA ; MSALYHIAQN ; ESPTLQSNEW ; 300: SDYFRNFVDS ; CLQKIPQDRP ; TSEELLKHIF ; VLRERPETVL ; IDLIQRTKDA ; 350: VRELDNLQYR ; KMKKLLFQEA ; HNGPAVEAQE ; EEEEQDHGVG ; RTGTVNSVGS ; 400: NQSIPSMSIS ; ASSQSSSVNS ; LPDVSDDKSE ; LDMMEGDHTV ; MSNSSVIHLK ; 450: PEEENYREEG ; DPRTRASDPQ ; SPPQVSRHKS ; HYRNREHFAT ; IRTASLVTRQ ; 500: MQEHEQDSEL ; REQMSGYKRM ; RRQHQKQLMT ; LENKLKAEMD ; EHRLRLDKDL ; 550: ETQRNNFAAE ; MEKLIKKHQA ; AMEKEAKVMS ; NEEKKFQQHI ; QAQQKKELNS ; 600: FLESQKREYK ; LRKEQLKEEL ; NENQSTPKKE ; KQEWLSKQKE ; NIQHFQAEEE ; 650: ANLLRRQRQY ; LELECRRFKR ; RMLLGRHNLE ; QDLVREELNK ; RQTQKDLEHA ; 700: MLLRQHESMQ ; ELEFRHLNTI ; QKMRCELIRL ; QHQTELTNQL ; EYNKRREREL ; 750: RRKHVMEVRQ ; QPKSLKSKEL ; QIKKQFQDTC ; KIQTRQYKAL ; RNHLLETTPK ; 800: SEHKAVLKRL ; KEEQTRKLAI ; LAEQYDHSIN ; EMLSTQALRL ; DEAQEAECQV ; 850: LKMQLQQELE ; LLNAYQSKIK ; MQAEAQHDRE ; LRELEQRVSL ; RRALLEQKIE ; 900: EEMLALQNER ; TERIRSLLER ; QAREIEAFDS ; ESMRLGFSNM ; VLSNLSPEAF ; 950: SHSYPGASGW ; SHNPTGGPGP ; HWGHPMGGPP ; QAWGHPMQGG ; PQPWGHPSGP ; 1000: MQGVPRGSSM ; GVRNSPQALR ; RTASGGRTEQ ; GMSRSTSVTS ; QISNGSHMSY ; 1001: T
Sequence Length	1001
String	Q7L7X3
Sub Unit	Self-associates. Interacts with MAP2K3 (By similarity). Interacts with SPRED1 and TESK1. Interacts with MAP3K7.

Uniprot	Q7L7X3
Gene Name	TAOK1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:57551
Unigene	Hs.597434

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810107	E2238h	96T	$736		Add to Cart

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