This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
Specificity
Natural and recombinant Human Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Subcellular Location
Nucleus membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Sarcoplasmic reticulum membrane Multi-pass membrane protein