G-alpha-interacting protein ; GAIP ; GAIP ; GNAI3IP
Categories
Elisa
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Specificity
Natural and recombinant Human Regulator of G-protein signaling 19