Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes.
Specificity
Natural and recombinant Human Ras-related protein Rab-14
Subcellular Location
Early endosome membrane Lipid-anchor Cytoplasmic side Golgi apparatus membrane Lipid-anchor Cytoplasmic side Golgi apparatus trans-Golgi network membrane Lipid-anchor Cytoplasmic side