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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Ras-related GTP-binding protein A

SKU : BHE13809982

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3277h
Alternative Names	Adenovirus E3 14.7 kDa-interacting protein 1 ; FIP-1
Categories	Elisa
Function	Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Specificity	Natural and recombinant Human Ras-related GTP-binding protein A
Subcellular Location	Cytoplasm Nucleus Lysosome Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.
Entryname	RRAGA_HUMAN
Platform	PF04670
Protein Name	Ras-related GTP-binding protein A
Sequence	50: MPNTAMKKKV ; LLMGKSGSGK ; TSMRSIIFAN ; YIARDTRRLG ; ATIDVEHSHV ; 100: RFLGNLVLNL ; WDCGGQDTFM ; ENYFTSQRDN ; IFRNVEVLIY ; VFDVESRELE ; 150: KDMHYYQSCL ; EAILQNSPDA ; KIFCLVHKMD ; LVQEDQRDLI ; FKEREEDLRR ; 200: LSRPLECACF ; RTSIWDETLY ; KAWSSIVYQL ; IPNVQQLEMN ; LRNFAQIIEA ; 250: DEVLLFERAT ; FLVISHYQCK ; EQRDVHRFEK ; ISNIIKQFKL ; SCSKLAASFQ ; 300: SMEVRNSNFA ; AFIDIFTSNT ; YVMVVMSDPS ; IPSAATLINI ; RNARKHFEKL ; 313: ERVDGPKHSL ; LMR
Sequence Length	313
String	Q7L523
Sub Unit	Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein.

Uniprot	Q7L523
Gene Name	RRAGA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10670
Unigene	Hs.743260

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809982	E3277h	96T	$736		Add to Cart

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