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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Ras-related C3 botulinum toxin substrate 1

SKU : BHE13808582

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15264h
Alternative Names	Cell migration-inducing gene 5 protein ; Ras-like protein TC25 ; p21-Rac1 ; TC25 ; MIG5
Categories	Elisa
Function	Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction.
Specificity	Natural and recombinant Human Ras-related C3 botulinum toxin substrate 1
Subcellular Location	Cell membrane Lipid-anchor Cytoplasmic side Melanosome Inner surface of plasma membrane possibly with attachment requiring prenylation of the C-terminal cysteine (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Entryname	RAC1_HUMAN
Platform	PF00071
Protein Name	Ras-related C3 botulinum toxin substrate 1
Sequence	50: MQAIKCVVVG ; DGAVGKTCLL ; ISYTTNAFPG ; EYIPTVFDNY ; SANVMVDGKP ; 100: VNLGLWDTAG ; QEDYDRLRPL ; SYPQTDVFLI ; CFSLVSPASF ; ENVRAKWYPE ; 150: VRHHCPNTPI ; ILVGTKLDLR ; DDKDTIEKLK ; EKKLTPITYP ; QGLAMAKEIG ; 192: AVKYLECSAL ; TQRGLKTVFD ; EAIRAVLCPP ; PVKKRKRKCL ; LL
Sequence Length	192
String	P63000
Sub Unit	Interacts with the GEF proteins PREX1, RASGRF2, DOCK1, DOCK2 and DOCK7, which promote the exchange between GDP and GTP, and therefore activate it. Interacts with PARD6A, PARD6B and PARD6G in a GTP-dependent manner. Part of a quaternary complex containing PARD3, some PARD6 protein (PARD6A, PARD6B or PARD6G) and some atypical PKC protein (PRKCI or PRKCZ), which plays a central role in epithelial cell polarization. Found in a trimeric complex composed of DOCK1 and ELMO1, which plays a central role in phagocytosis of apoptotic cells. Interacts with RALBP1 via its effector domain. Interacts with PLXNB1. Probably found in a ternary complex composed of DSCAM, PAK1 and RAC1. Interacts with DSCAM; the interaction requires PAK1. Part of a complex with MAP2K3, MAP3K3, CCM2 and DEF6. Interacts with BAIAP2, BAIAP2L1, CYFIP1/SRA-1 and DEF6. Interacts with Y.pseudotuberculosis YPKA and PLCB2. Interacts with NOXA1. Interacts with ARHGEF2. Interacts with NISCH (By similarity). Interacts with TBC1D2. Interacts with UNKL. Interacts with USP6. Interacts with SPATA13. Interacts with ARHGEF16; mediates activation of RAC1 by EPHA2. Interacts with ITGB4.

Uniprot	P63000
Gene Name	RAC1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5879
Unigene	Hs.413812

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808582	E15264h	96T	$736		Add to Cart

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