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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Pyridoxal phosphate phosphatase

SKU : BHE13809615

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1712h
Alternative Names	Chronophin ; CIN ; PLP ; PLPP
Categories	Elisa
Function	Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP.
Specificity	Natural and recombinant Human Pyridoxal phosphate phosphatase
Subcellular Location	Cytoplasm cytosol Cytoplasm cytoskeleton Cell projection ruffle membrane Peripheral membrane protein Cytoplasmic side Cell projection lamellipodium membrane Peripheral membrane protein Cytoplasmic side Cell membrane Peripheral membrane protein Cytoplasmic side Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Diffusely distributed throughout the cytosol during pro-metaphase and metaphase. Detected at the dynamic cell poles during telophase. Detected at the cleavage furrow and contractile ring during cytokinesis. Transiently detected at the plasma membrane in late stages of cytokinesis. Detected at the midbody.
Detection Range	0.625-40ng/mL
Entryname	PLPP_HUMAN
Method Type	Sandwich
Platform	PF00702
Protein Name	Pyridoxal phosphate phosphatase
Sensitivity	0.176ng/mL
Sequence	50: MARCERLRGA ; ALRDVLGRAQ ; GVLFDCDGVL ; WNGERAVPGA ; PELLERLARA ; 100: GKAALFVSNN ; SRRARPELAL ; RFARLGFGGL ; RAEQLFSSAL ; CAARLLRQRL ; 150: PGPPDAPGAV ; FVLGGEGLRA ; ELRAAGLRLA ; GDPSAGDGAA ; PRVRAVLVGY ; 200: DEHFSFAKLR ; EACAHLRDPE ; CLLVATDRDP ; WHPLSDGSRT ; PGTGSLAAAV ; 250: ETASGRQALV ; VGKPSPYMFE ; CITENFSIDP ; ARTLMVGDRL ; ETDILFGHRC ; 296: GMTTVLTLTG ; VSRLEEAQAY ; LAAGQHDLVP ; HYYVESIADL ; TEGLED
Sequence Length	296
String	Q96GD0
Sub Unit	Homodimer.

Uniprot	Q96GD0
Gene Name	PDXP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:57026
Unigene	Hs.632762

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809615	E1712h	96T	$736		Add to Cart

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