ELISA Kit for Human Protein prune homolog

Mfr.No.	E6149h
Alternative Names	Drosophila-related expressed sequence 17 ; DRES-17 ; HTcD37
Categories	Elisa
Function	Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
Specificity	Natural and recombinant Human Protein prune homolog
Subcellular Location	Cytoplasm Nucleus Cell junction focal adhesion In some transfected cells a nuclear staining is also observed.
Detection Range	0.312-20ng/mL
Entryname	PRUNE_HUMAN
Method Type	Sandwich
Platform	PF01368
Protein Name	Protein prune homolog
Sensitivity	0.121ng/mL
Sequence	50: MEDYLQGCRA ; ALQESRPLHV ; VLGNEACDLD ; STVSALALAF ; YLAKTTEAEE ; 100: VFVPVLNIKR ; SELPLRGDIV ; FFLQKVHIPE ; SILIFRDEID ; LHALYQAGQL ; 150: TLILVDHHIL ; SKSDTALEEA ; VAEVLDHRPI ; EPKHCPPCHV ; SVELVGSCAT ; 200: LVTERILQGA ; PEILDRQTAA ; LLHGTIILDC ; VNMDLKIGKA ; TPKDSKYVEK ; 250: LEALFPDLPK ; RNDIFDSLQK ; AKFDVSGLTT ; EQMLRKDQKT ; IYRQGVKVAI ; 300: SAIYMDLEAF ; LQRSNLLADL ; HAFCQAHSYD ; VLVAMTIFFN ; THNEPVRQLA ; 350: IFCPHVALQT ; TICEVLERSH ; SPPLKLTPAS ; STHPNLHAYL ; QGNTQVSRKK ; 400: LLPLLQEALS ; AYFDSMKIPS ; GQPETADVSR ; EQVDKELDRA ; SNSLISGLSQ ; 450: DEEDPPLPPT ; PMNSLVDECP ; LDQGLPKLSA ; EAVFEKCSQI ; SLSQSTTASL ; 453: SKK
Sequence Length	453
String	Q86TP1
Sub Unit	Homooligomer. Able to homodimerize via its C-terminal domain. Interacts with NME1. Interacts with GSK3; at focal adhesion complexes where paxillin and vinculin are colocalized.

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