ELISA Kit for Human Protein Mdm4

Mfr.No.	E12870h
Alternative Names	Double minute 4 protein ; Mdm2-like p53-binding protein ; Protein Mdmx ; p53-binding protein Mdm4 ; MDMX
Categories	Elisa
Function	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Specificity	Natural and recombinant Human Protein Mdm4
Subcellular Location	Nucleus
Detection Range	0.78-50ng/mL
Entryname	MDM4_HUMAN
Method Type	Sandwich
Platform	PF02201
Protein Name	Protein Mdm4
Sensitivity	0.44ng/mL
Sequence	50: MTSFSTSAQC ; STSDSACRIS ; PGQINQVRPK ; LPLLKILHAA ; GAQGEMFTVK ; 100: EVMHYLGQYI ; MVKQLYDQQE ; QHMVYCGGDL ; LGELLGRQSF ; SVKDPSPLYD ; 150: MLRKNLVTLA ; TATTDAAQTL ; ALAQDHSMDI ; PSQDQLKQSA ; EESSTSRKRT ; 200: TEDDIPTLPT ; SEHKCIHSRE ; DEDLIENLAQ ; DETSRLDLGF ; EEWDVAGLPW ; 250: WFLGNLRSNY ; TPRSNGSTDL ; QTNQDVGTAI ; VSDTTDDLWF ; LNESVSEQLG ; 300: VGIKVEAADT ; EQTSEEVGKV ; SDKKVIEVGK ; NDDLEDSKSL ; SDDTDVEVTS ; 350: EDEWQCTECK ; KFNSPSKRYC ; FRCWALRKDW ; YSDCSKLTHS ; LSTSDITAIP ; 400: EKENEGNDVP ; DCRRTISAPV ; VRPKDAYIKK ; ENSKLFDPCN ; SVEFLDLAHS ; 450: SESQETISSM ; GEQLDNLSEQ ; RTDTENMEDC ; QNLLKPCSLC ; EKRPRDGNII ; 490: HGRTGHLVTC ; FHCARRLKKA ; GASCPICKKE ; IQLVIKVFIA ;
Sequence Length	490
String	O15151
Sub Unit	Interacts with MDM2, TP53, TP73 and USP2. Found in a trimeric complex with UPB2, MDM2 and MDM4.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806685	E12870h	96T	$736		Add to Cart