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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Prolyl endopeptidase FAP

SKU : BHE13810843

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9685h
Alternative Names	170 kDa melanoma membrane-bound gelatinase ; Dipeptidyl peptidase FAP ; 3.4.14.5 ; Fibroblast activation protein alpha ; FAPalpha ; Gelatine degradation protease FAP ; 3.4.21.- ; Integral membrane serine protease ; Post-proline cleaving enzyme ; Serine integral membrane protease ; SIMP ; Surface-expressed protease ; Seprase
Categories	Elisa
Function	In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers.
Specificity	Natural and recombinant Human Prolyl endopeptidase FAP
Subcellular Location	Cell membrane Single-pass type II membrane protein Cell projection lamellipodium membrane Single-pass type II membrane protein Cell projection invadopodium membrane Single-pass type II membrane protein Found in cell surface lamellipodia, invadopodia and on shed vesicles. Colocalized with DPP4 in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with DPP4 on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma.
Detection Range	78-5000pg/ml
Entryname	SEPR_HUMAN
Method Type	Sandwich
Platform	PF00930
Protein Name	Prolyl endopeptidase FAP
Sensitivity	40pg/mL
Sequence	50: MKTWVKIVFG ; VATSAVLALL ; VMCIVLRPSR ; VHNSEENTMR ; ALTLKDILNG ; 100: TFSYKTFFPN ; WISGQEYLHQ ; SADNNIVLYN ; IETGQSYTIL ; SNRTMKSVNA ; 150: SNYGLSPDRQ ; FVYLESDYSK ; LWRYSYTATY ; YIYDLSNGEF ; VRGNELPRPI ; 200: QYLCWSPVGS ; KLAYVYQNNI ; YLKQRPGDPP ; FQITFNGREN ; KIFNGIPDWV ; 250: YEEEMLATKY ; ALWWSPNGKF ; LAYAEFNDTD ; IPVIAYSYYG ; DEQYPRTINI ; 300: PYPKAGAKNP ; VVRIFIIDTT ; YPAYVGPQEV ; PVPAMIASSD ; YYFSWLTWVT ; 350: DERVCLQWLK ; RVQNVSVLSI ; CDFREDWQTW ; DCPKTQEHIE ; ESRTGWAGGF ; 400: FVSTPVFSYD ; AISYYKIFSD ; KDGYKHIHYI ; KDTVENAIQI ; TSGKWEAINI ; 450: FRVTQDSLFY ; SSNEFEEYPG ; RRNIYRISIG ; SYPPSKKCVT ; CHLRKERCQY ; 500: YTASFSDYAK ; YYALVCYGPG ; IPISTLHDGR ; TDQEIKILEE ; NKELENALKN ; 550: IQLPKEEIKK ; LEVDEITLWY ; KMILPPQFDR ; SKKYPLLIQV ; YGGPCSQSVR ; 600: SVFAVNWISY ; LASKEGMVIA ; LVDGRGTAFQ ; GDKLLYAVYR ; KLGVYEVEDQ ; 650: ITAVRKFIEM ; GFIDEKRIAI ; WGWSYGGYVS ; SLALASGTGL ; FKCGIAVAPV ; 700: SSWEYYASVY ; TERFMGLPTK ; DDNLEHYKNS ; TVMARAEYFR ; NVDYLLIHGT ; 750: ADDNVHFQNS ; AQIAKALVNA ; QVDFQAMWYS ; DQNHGLSGLS ; TNHLYTHMTH ; 760: FLKQCFSLSD ;
Sequence Length	760
String	Q12884
Sub Unit	Homodimer, or heterodimer with DPP4. The monomer is inactive.

Uniprot	Q12884
Gene Name	FAP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2191
Unigene	Hs.654370

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810843	E9685h	96T	$736		Add to Cart

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