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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Poliovirus receptor-related protein 3

SKU : BHE13809335

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9234h
Alternative Names	CDw113 ; Nectin-3 ; PRR3 ; CD113
Categories	Elisa
Function	Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.
Specificity	Natural and recombinant Human Poliovirus receptor-related protein 3
Subcellular Location	Cell membrane Single-pass membrane protein
Entryname	PVRL3_HUMAN
Platform	PF08205
Protein Name	Poliovirus receptor-related protein 3
Sequence	50: MARTLRPSPL ; CPGGGKAQLS ; SASLLGAGLL ; LQPPTPPPLL ; LLLFPLLLFS ; 100: RLCGALAGPI ; IVEPHVTAVW ; GKNVSLKCLI ; EVNETITQIS ; WEKIHGKSSQ ; 150: TVAVHHPQYG ; FSVQGEYQGR ; VLFKNYSLND ; ATITLHNIGF ; SDSGKYICKA ; 200: VTFPLGNAQS ; STTVTVLVEP ; TVSLIKGPDS ; LIDGGNETVA ; AICIAATGKP ; 250: VAHIDWEGDL ; GEMESTTTSF ; PNETATIISQ ; YKLFPTRFAR ; GRRITCVVKH ; 300: PALEKDIRYS ; FILDIQYAPE ; VSVTGYDGNW ; FVGRKGVNLK ; CNADANPPPF ; 350: KSVWSRLDGQ ; WPDGLLASDN ; TLHFVHPLTF ; NYSGVYICKV ; TNSLGQRSDQ ; 400: KVIYISDPPT ; TTTLQPTIQW ; HPSTADIEDL ; ATEPKKLPFP ; LSTLATIKDD ; 450: TIATIIASVV ; GGALFIVLVS ; VLAGIFCYRR ; RRTFRGDYFA ; KNYIPPSDMQ ; 500: KESQIDVLQQ ; DELDSYPDSV ; KKENKNPVNN ; LIRKDYLEEP ; EKTQWNNVEN ; 549: LNRFERPMDY ; YEDLKMGMKF ; VSDEHYDENE ; DDLVSHVDGS ; VISRREWYV
Sequence Length	549
String	Q9NQS3
Sub Unit	Cis- and trans-homodimer. Can form trans-heterodimers with PVRL1/nectin-1, PVRL2/nectin-2, PVR, IGSF4B/Necl-1 and with IGSF4. Interacts with MLLT4/afadin. Binds with low affinity to TIGIT.

Uniprot	Q9NQS3
Gene Name	PVRL3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:25945
Unigene	Hs.293917

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809335	E9234h	96T	$736		Add to Cart

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