ELISA Kit for Human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

Mfr.No.	E7189h
Alternative Names	Peptidyl-prolyl cis-trans isomerase Pin1 ; PPIase Pin1 ; Rotamase Pin1
Categories	Elisa
Function	Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK.
Specificity	Natural and recombinant Human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Subcellular Location	Nucleus Co-localizes with NEK6 in the nucleus.
Detection Range	78-5000pg/mL
Entryname	PIN1_HUMAN
Method Type	Sandwich
Platform	PF00639
Protein Name	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Sensitivity	34pg/mL
Sequence	50: MADEEKLPPG ; WEKRMSRSSG ; RVYYFNHITN ; ASQWERPSGN ; SSSGGKNGQG ; 100: EPARVRCSHL ; LVKHSQSRRP ; SSWRQEKITR ; TKEEALELIN ; GYIQKIKSGE ; 150: EDFESLASQF ; SDCSSAKARG ; DLGAFSRGQM ; QKPFEDASFA ; LRTGEMSGPV ; 163: FTDSGIHIIL ; RTE
Sequence Length	163
String	Q13526
Sub Unit	Interacts with STIL (By similarity). Interacts with KIF20B. Interacts with NEK6. Interacts (via WW domain) with PRKX. Interacts with BTK.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808805	E7189h	96T	$736		Add to Cart