JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Peptidyl-prolyl cis-trans isomerase FKBP8

SKU : BHE13804288

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E11198h
Alternative Names	38 kDa FK506-binding protein ; 38 kDa FKBP ; FK506-binding protein 8 ; FKBP-8 ; FKBPR38 ; Rotamase ; FKBP38
Categories	Elisa
Function	Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
Specificity	Natural and recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8
Subcellular Location	Mitochondrion membrane Single-pass membrane protein Cytoplasmic side
Detection Range	0.156-10ng/mL
Entryname	FKBP8_HUMAN
Method Type	Sandwich
Platform	PF00254
Protein Name	Peptidyl-prolyl cis-trans isomerase FKBP8
Sensitivity	0.078ng/ml
Sequence	50: MASCAEPSEP ; SAPLPAGVPP ; LEDFEVLDGV ; EDAEGEEEEE ; EEEEEEDDLS ; 100: ELPPLEDMGQ ; PPAEEAEQPG ; ALAREFLAAM ; EPEPAPAPAP ; EEWLDILGNG ; 150: LLRKKTLVPG ; PPGSSRPVKG ; QVVTVHLQTS ; LENGTRVQEE ; PELVFTLGDC ; 200: DVIQALDLSV ; PLMDVGETAM ; VTADSKYCYG ; PQGRSPYIPP ; HAALCLEVTL ; 250: KTAVDGPDLE ; MLTGQERVAL ; ANRKRECGNA ; HYQRADFVLA ; ANSYDLAIKA ; 300: ITSSAKVDMT ; FEEEAQLLQL ; KVKCLNNLAA ; SQLKLDHYRA ; ALRSCSLVLE ; 350: HQPDNIKALF ; RKGKVLAQQG ; EYSEAIPILR ; AALKLEPSNK ; TIHAELSKLV ; 400: KKHAAQRSTE ; TALYRKMLGN ; PSRLPAKCPG ; KGAWSIPWKW ; LFGATAVALG ; 412: GVALSVVIAA ; RN
Sequence Length	412
String	Q14318
Sub Unit	Homomultimers or heteromultimers (Potential). Forms heterodimer with calmodulin. When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L). Does not bind and inhibit calcineurin. Interacts with HCV NS5A. Interacts with ZFYVE27; may negatively regulate ZFYVE27 phosphorylation.

Uniprot	Q14318
Gene Name	FKBP8
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23770
Unigene	Hs.173464

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13804288	E11198h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.