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Home / Assay Kits / ELISA Kits

ELISA Kit for Human PC4 and SFRS1-interacting protein

SKU : BHE13809337

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15031h
Alternative Names	CLL-associated antigen KW-7 ; Dense fine speckles 70 kDa protein ; DFS 70 ; Lens epithelium-derived growth factor ; Transcriptional coactivator p75/p52 ; DFS70 ; LEDGF ; PSIP2
Categories	Elisa
Function	Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
Specificity	Natural and recombinant Human PC4 and SFRS1-interacting protein
Subcellular Location	Nucleus Remains chromatin-associated throughout the cell cycle.
Detection Range	78-5000pg/mL
Entryname	PSIP1_HUMAN
Method Type	Sandwich
Platform	PF11467
Protein Name	PC4 and SFRS1-interacting protein
Sensitivity	23pg/ml
Sequence	50: MTRDFKPGDL ; IFAKMKGYPH ; WPARVDEVPD ; GAVKPPTNKL ; PIFFFGTHET ; 100: AFLGPKDIFP ; YSENKEKYGK ; PNKRKGFNEG ; LWEIDNNPKV ; KFSSQQAATK ; 150: QSNASSDVEV ; EEKETSVSKE ; DTDHEEKASN ; EDVTKAVDIT ; TPKAARRGRK ; 200: RKAEKQVETE ; EAGVVTTATA ; SVNLKVSPKR ; GRPAATEVKI ; PKPRGRPKMV ; 250: KQPCPSESDI ; ITEEDKSKKK ; GQEEKQPKKQ ; PKKDEEGQKE ; EDKPRKEPDK ; 300: KEGKKEVESK ; RKNLAKTGVT ; STSDSEEEGD ; DQEGEKKRKG ; GRNFQTAHRR ; 350: NMLKGQHEKE ; AADRKRKQEE ; QMETEQQNKD ; EGKKPEVKKV ; EKKRETSMDS ; 400: RLQRIHAEIK ; NSLKIDNLDV ; NRCIEALDEL ; ASLQVTMQQA ; QKHTEMITTL ; 450: KKIRRFKVSQ ; VIMEKSTMLY ; NKFKNMFLVG ; EGDSVITQVL ; NKSLAEQRQH ; 500: EEANKTKDQG ; KKGPNKKLEK ; EQTGSKTLNG ; GSDAQDGNQP ; QHNGESNEDS ; 530: KDNHEASTKK ; KPSSEERETE ; ISLKDSTLDN ;
Sequence Length	530
String	O75475
Sub Unit	Monomer. Interacts with IFRD1/PC4. Isoform 2 interacts with SFRS1. Isoform 1 interacts POGZ and CDCA7L. Isoform 1 interacts with lentiviral integrase and acts as a chromatin tethering factor to the chromosomal DNA. Isoform 1 interacts in particular with the human HIV-1 integrase protein (HIV-1 IN), determining its nuclear localization, its tight association with chromatin and its protection from the proteasome. Isoform 1 interacts also with HIV-2 IN. Isoform 2 does not interact with HIV-1 IN.

Uniprot	O75475
Gene Name	PSIP1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:11168
Unigene	Hs.658434

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809337	E15031h	96T	$736		Add to Cart

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