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ELISA Kit for Human Pappalysin-1

SKU : BHE13808466

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0800h
Alternative Names	Insulin-like growth factor-dependent IGF-binding protein 4 protease ; IGF-dependent IGFBP-4 protease ; Pregnancy-associated plasma protein A ; PAPP-A
Categories	Elisa
Function	Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Specificity	Natural and recombinant Human Pappalysin-1
Subcellular Location	Secreted
Detection Range	62.5-4000pg/mL
Entryname	PAPP1_HUMAN
Method Type	Sandwich
Platform	PF00066
Protein Name	Pappalysin-1
Sensitivity	31.2pg/mL
Sequence	50: MRLWSWVLHL ; GLLSAALGCG ; LAERPRRARR ; DPRAGRPPRP ; AAGPATCATR ; 100: AARGRRASPP ; PPPPPGGAWE ; AVRVPRRRQQ ; REARGATEEP ; SPPSRALYFS ; 150: GRGEQLRLRA ; DLELPRDAFT ; LQVWLRAEGG ; QRSPAVITGL ; YDKCSYISRD ; 200: RGWVVGIHTI ; SDQDNKDPRY ; FFSLKTDRAR ; QVTTINAHRS ; YLPGQWVYLA ; 250: ATYDGQFMKL ; YVNGAQVATS ; GEQVGGIFSP ; LTQKCKVLML ; GGSALNHNYR ; 300: GYIEHFSLWK ; VARTQREILS ; DMETHGAHTA ; LPQLLLQENW ; DNVKHAWSPM ; 350: KDGSSPKVEF ; SNAHGFLLDT ; SLEPPLCGQT ; LCDNTEVIAS ; YNQLSSFRQP ; 400: KVVRYRVVNL ; YEDDHKNPTV ; TREQVDFQHH ; QLAEAFKQYN ; ISWELDVLEV ; 450: SNSSLRRRLI ; LANCDISKIG ; DENCDPECNH ; TLTGHDGGDC ; RHLRHPAFVK ; 500: KQHNGVCDMD ; CNYERFNFDG ; GECCDPEITN ; VTQTCFDPDS ; PHRAYLDVNE ; 550: LKNILKLDGS ; THLNIFFAKS ; SEEELAGVAT ; WPWDKEALMH ; LGGIVLNPSF ; 600: YGMPGHTHTM ; IHEIGHSLGL ; YHVFRGISEI ; QSCSDPCMET ; EPSFETGDLC ; 650: NDTNPAPKHK ; SCGDPGPGND ; TCGFHSFFNT ; PYNNFMSYAD ; DDCTDSFTPN ; 700: QVARMHCYLD ; LVYQGWQPSR ; KPAPVALAPQ ; VLGHTTDSVT ; LEWFPPIDGH ; 750: FFERELGSAC ; HLCLEGRILV ; QYASNASSPM ; PCSPSGHWSP ; REAEGHPDVE ; 800: QPCKSSVRTW ; SPNSAVNPHT ; VPPACPEPQG ; CYLELEFLYP ; LVPESLTIWV ; 850: TFVSTDWDSS ; GAVNDIKLLA ; VSGKNISLGP ; QNVFCDVPLT ; IRLWDVGEEV ; 900: YGIQIYTLDE ; HLEIDAAMLT ; STADTPLCLQ ; CKPLKYKVVR ; DPPLQMDVAS ; 950: ILHLNRKFVD ; MDLNLGSVYQ ; YWVITISGTE ; ESEPSPAVTY ; IHGSGYCGDG ; 1000: IIQKDQGEQC ; DDMNKINGDG ; CSLFCRQEVS ; FNCIDEPSRC ; YFHDGDGVCE ; 1050: EFEQKTSIKD ; CGVYTPQGFL ; DQWASNASVS ; HQDQQCPGWV ; IIGQPAASQV ; 1100: CRTKVIDLSE ; GISQHAWYPC ; TISYPYSQLA ; QTTFWLRAYF ; SQPMVAAAVI ; 1150: VHLVTDGTYY ; GDQKQETISV ; QLLDTKDQSH ; DLGLHVLSCR ; NNPLIIPVVH ; 1200: DLSQPFYHSQ ; AVRVSFSSPL ; VAISGVALRS ; FDNFDPVTLS ; SCQRGETYSP ; 1250: AEQSCVHFAC ; EKTDCPELAV ; ENASLNCSSS ; DRYHGAQCTV ; SCRTGYVLQI ; 1300: RRDDELIKSQ ; TGPSVTVTCT ; EGKWNKQVAC ; EPVDCSIPDH ; HQVYAASFSC ; 1350: PEGTTFGSQC ; SFQCRHPAQL ; KGNNSLLTCM ; EDGLWSFPEA ; LCELMCLAPP ; 1400: PVPNADLQTA ; RCRENKHKVG ; SFCKYKCKPG ; YHVPGSSRKS ; KKRAFKTQCT ; 1450: QDGSWQEGAC ; VPVTCDPPPP ; KFHGLYQCTN ; GFQFNSECRI ; KCEDSDASQG ; 1500: LGSNVIHCRK ; DGTWNGSFHV ; CQEMQGQCSV ; PNELNSNLKL ; QCPDGYAIGS ; 1550: ECATSCLDHN ; SESIILPMNV ; TVRDIPHWLN ; PTRVERVVCT ; AGLKWYPHPA ; 1600: LIHCVKGCEP ; FMGDNYCDAI ; NNRAFCNYDG ; GDCCTSTVKT ; KKVTPFPMSC ; 1627: DLQGDCACRD ; PQAQEHSRKD ; LRGYSHG
Sequence Length	1627
String	Q13219
Sub Unit	Homodimer; disulfide-linked. In pregnancy serum, predominantly found as a disulfide-linked 2:2 heterotetramer with the proform of PRG2.

Uniprot	Q13219
Gene Name	PAPPA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5069
Unigene	Hs.643599

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808466	E0800h	96T	$536		Add to Cart

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