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Home / Assay Kits / ELISA Kits

ELISA Kit for Human NACHT, LRR and PYD domains-containing protein 3

SKU : BHE13806853

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14531h
Alternative Names	Angiotensin/vasopressin receptor AII/AVP-like ; Caterpiller protein 1.1 ; CLR1.1 ; Cold autoinflammatory syndrome 1 protein ; Cryopyrin ; PYRIN-containing APAF1-like protein 1 ; C1orf7 ; CIAS1 ; NALP3 ; PYPAF1
Categories	Elisa
Function	May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Specificity	Natural and recombinant Human NACHT, LRR and PYD domains-containing protein 3
Subcellular Location	Cytoplasm
Detection Range	0.156-10ng/mL
Entryname	NALP3_HUMAN
Method Type	Sandwich
Platform	PF02758
Protein Name	NACHT, LRR and PYD domains-containing protein 3
Sensitivity	0.078ng/mL
Sequence	50: MKMASTRCKL ; ARYLEDLEDV ; DLKKFKMHLE ; DYPPQKGCIP ; LPRGQTEKAD ; 100: HVDLATLMID ; FNGEEKAWAM ; AVWIFAAINR ; RDLYEKAKRD ; EPKWGSDNAR ; 150: VSNPTVICQE ; DSIEEEWMGL ; LEYLSRISIC ; KMKKDYRKKY ; RKYVRSRFQC ; 200: IEDRNARLGE ; SVSLNKRYTR ; LRLIKEHRSQ ; QEREQELLAI ; GKTKTCESPV ; 250: SPIKMELLFD ; PDDEHSEPVH ; TVVFQGAAGI ; GKTILARKMM ; LDWASGTLYQ ; 300: DRFDYLFYIH ; CREVSLVTQR ; SLGDLIMSCC ; PDPNPPIHKI ; VRKPSRILFL ; 350: MDGFDELQGA ; FDEHIGPLCT ; DWQKAERGDI ; LLSSLIRKKL ; LPEASLLITT ; 400: RPVALEKLQH ; LLDHPRHVEI ; LGFSEAKRKE ; YFFKYFSDEA ; QARAAFSLIQ ; 450: ENEVLFTMCF ; IPLVCWIVCT ; GLKQQMESGK ; SLAQTSKTTT ; AVYVFFLSSL ; 500: LQPRGGSQEH ; GLCAHLWGLC ; SLAADGIWNQ ; KILFEESDLR ; NHGLQKADVS ; 550: AFLRMNLFQK ; EVDCEKFYSF ; IHMTFQEFFA ; AMYYLLEEEK ; EGRTNVPGSR ; 600: LKLPSRDVTV ; LLENYGKFEK ; GYLIFVVRFL ; FGLVNQERTS ; YLEKKLSCKI ; 650: SQQIRLELLK ; WIEVKAKAKK ; LQIQPSQLEL ; FYCLYEMQEE ; DFVQRAMDYF ; 700: PKIEINLSTR ; MDHMVSSFCI ; ENCHRVESLS ; LGFLHNMPKE ; EEEEEKEGRH ; 750: LDMVQCVLPS ; SSHAACSHGL ; VNSHLTSSFC ; RGLFSVLSTS ; QSLTELDLSD ; 800: NSLGDPGMRV ; LCETLQHPGC ; NIRRLWLGRC ; GLSHECCFDI ; SLVLSSNQKL ; 850: VELDLSDNAL ; GDFGIRLLCV ; GLKHLLCNLK ; KLWLVSCCLT ; SACCQDLASV ; 900: LSTSHSLTRL ; YVGENALGDS ; GVAILCEKAK ; NPQCNLQKLG ; LVNSGLTSVC ; 950: CSALSSVLST ; NQNLTHLYLR ; GNTLGDKGIK ; LLCEGLLHPD ; CKLQVLELDN ; 1000: CNLTSHCCWD ; LSTLLTSSQS ; LRKLSLGNND ; LGDLGVMMFC ; EVLKQQSCLL ; 1036: QNLGLSEMYF ; NYETKSALET ; LQEEKPELTV ; VFEPSW
Sequence Length	1036
String	Q96P20
Sub Unit	Interacts with PYCARD/ASC. Part of the NALP3 inflammasome complex which is involved in activation of caspase-1 and caspase-5, leading to processing of IL1B and IL18.

Uniprot	Q96P20
Gene Name	NLRP3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:114548
Unigene	Hs.159483

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806853	E14531h	96T	$736		Add to Cart

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