Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.
Specificity
Natural and recombinant Human N(G),N(G)-dimethylarginine dimethylaminohydrolase 1