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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Myeloid cell surface antigen CD33

SKU : BHE13801747

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15134h
Alternative Names	Sialic acid-binding Ig-like lectin 3 ; Siglec-3 ; gp67 ; CD33 ; SIGLEC3
Categories	Elisa
Function	Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Specificity	Natural and recombinant Human Myeloid cell surface antigen CD33
Subcellular Location	Cell membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	CD33_HUMAN
Method Type	Sandwich
Platform	PF00047
Protein Name	Myeloid cell surface antigen CD33
Sensitivity	39.6pg/mL
Sequence	50: MPLLLLLPLL ; WAGALAMDPN ; FWLQVQESVT ; VQEGLCVLVP ; CTFFHPIPYY ; 100: DKNSPVHGYW ; FREGAIISRD ; SPVATNKLDQ ; EVQEETQGRF ; RLLGDPSRNN ; 150: CSLSIVDARR ; RDNGSYFFRM ; ERGSTKYSYK ; SPQLSVHVTD ; LTHRPKILIP ; 200: GTLEPGHSKN ; LTCSVSWACE ; QGTPPIFSWL ; SAAPTSLGPR ; TTHSSVLIIT ; 250: PRPQDHGTNL ; TCQVKFAGAG ; VTTERTIQLN ; VTYVPQNPTT ; GIFPGDGSGK ; 300: QETRAGVVHG ; AIGGAGVTAL ; LALCLCLIFF ; IVKTHRRKAA ; RTAVGRNDTH ; 350: PTTGSASPKH ; QKKSKLHGPT ; ETSSCSGAAP ; TVEMDEELHY ; ASLNFHGMNP ; 364: SKDTSTEYSE ; VRTQ
Sequence Length	364
String	P20138
Sub Unit	Interacts with PTPN6/SHP-1 and PTPN11/SHP-2 upon phosphorylation.

Uniprot	P20138
Gene Name	CD33
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:945
Unigene	Hs.83731

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801747	E15134h	96T	$736		Add to Cart

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